Intracellular peptides (InPeps) generated by proteasomes were previously suggested as
putative natural regulators of protein–protein interactions (PPI). Here, the main aim was to …

Intracellular peptides (InPeps) generated by proteasomes were previously suggested as
putative natural regulators of protein–protein interactions (PPI). Here, the main aim was to …

Abstract FK506 binding protein 5 (FKBP5) belongs to a family of immunophilins named for
their ability to bind immunosuppressive drugs, also known as peptidyl-prolyl cis-trans …

Autophagy is a homeostatic process by which misfolded proteins, organelles and
cytoplasmic material are engulfed in autophagosomal vesicles and degraded through a …

Cancer therapy is limited, in part, by lack of specificity. Thus, identifying molecules that are
selectively expressed by, and relevant for, cancer cells is of paramount medical importance …

In this paper, we show some evidence that a member of the FK506-binding proteins,
FKBP25 is associated to diverse components that are part of several different intracellular …

Mammalian target of rapamycin (mTOR) signaling is a core pathway in cellular metabolism,
and control of the mTOR pathway by rapamycin shows potential for the treatment of …

ATG4B facilitates autophagy by promoting autophagosome maturation through the
reversible lipidation and delipidation of LC3. Recent reports have shown that …

The FK506 Binding Protein 51 (FKBP51) is an identified risk factor for a variety of psychiatric
disorders such as major depressive disorder as well as obesity and chronic pain …

Background FK506 binding protein 51 (FKBP51) is an Hsp90 co-chaperone and regulator of
the glucocorticoid receptor, and consequently of stress physiology. Clinical studies suggest …