[HTML][HTML] The interaction between social hierarchy and depression/anxiety: Involvement of glutamatergic pyramidal neurons in the medial prefrontal cortex (mPFC)

YY Yin, ZK Lai, JZ Yan, QQ Wei, B Wang, LM Zhang… - Neurobiology of …, 2023 - Elsevier
Social hierarchy greatly impacts physical and mental health, but the relationship between
social hierarchy and depression/anxiety and the underlying neural mechanism remain …

The effect of depressive-like behavior and antidepressant therapy on social behavior and hierarchy in rats

M Boyko, R Kutz, J Grinshpun, V Zvenigorodsky… - Behavioural brain …, 2019 - Elsevier
Background Depression is common and results in a significant morbidity and economic
burden. Depression is associated with pervasive impairments in social functioning, and …

Social defeat-induced Cingulate gyrus immediate-early gene expression and anxiolytic-like effect depend upon social rank

AH Basil, M Gross, R Rajkumar, M Kirby… - Brain Research …, 2018 - Elsevier
Social hierarchy is considered to impart an adaptive advantage to the species by reducing
long-term conflict between conspecifics. While social stratification is frequently established …

[HTML][HTML] Stress-induced changes in social dominance are scaled by AMPA-type glutamate receptor phosphorylation in the medial prefrontal cortex

MJ Park, BA Seo, B Lee, HS Shin, MG Kang - Scientific Reports, 2018 - nature.com
The establishment and maintenance of social dominance are critical for social stability and
the survival and health of individual animals. Stress lead to depression and a decrease in …

Social hierarchy differentially influences the anxiety-like behaviors and dendritic spine density in prefrontal cortex and limbic areas in male rats

Z Parvin, MR Afarinesh, N Hosseinmardi… - Behavioural Brain …, 2024 - Elsevier
Social hierarchy is a fundamental feature of social organization that can influence brain and
emotional processing regarding social ranks. Several areas, including the medial prefrontal …

The mouse that roared: neural mechanisms of social hierarchy

F Wang, HW Kessels, H Hu - Trends in neurosciences, 2014 - cell.com
Hierarchical social status greatly influences behavior and health. Human and animal studies
have begun to identify the brain regions that are activated during the formation of social …

Neural mechanisms linking social status and inflammatory responses to social stress

KA Muscatell, K Dedovic, GM Slavich… - Social cognitive and …, 2016 - academic.oup.com
Social stratification has important implications for health and well-being, with individuals
lower in standing in a hierarchy experiencing worse outcomes than those higher up the …

[HTML][HTML] Social defeat stress causes selective attenuation of neuronal activity in the ventromedial prefrontal cortex

R Abe, S Okada, R Nakayama, Y Ikegaya, T Sasaki - Scientific Reports, 2019 - nature.com
The ventromedial prefrontal cortex (vmPFC) plays key roles in higher cognitive abilities,
including mental representations and the regulation of emotion. Previous studies have …

[HTML][HTML] Role of medial prefrontal cortical neurons and oxytocin modulation in the establishment of social buffering

T Jung, M Jang, J Noh - Experimental Neurobiology, 2021 - ncbi.nlm.nih.gov
Fear-related behaviors are rigidly controlled by the medial prefrontal cortex (mPFC). The
mPFC is activated by the prosocial hormone oxytocin, which plays an important role in social …

Social dominance modulates stress-induced neural activity in medial prefrontal cortex projections to the basolateral amygdala

BN Dulka, KS Bress, JA Grizzell, MA Cooper - Neuroscience, 2018 - Elsevier
Stress is a contributing factor in the etiology of several mood and anxiety disorders, and
social defeat models are used to investigate the biological basis of stress-related …