[18F]FDG-PET/CT to prevent futile surgery in indeterminate thyroid nodules: a blinded, randomised controlled multicentre trial

EJ de Koster, LF de Geus-Oei, AH Brouwers… - European Journal of …, 2022 - Springer
Purpose To assess the impact of an [18 F] FDG-PET/CT-driven diagnostic workup to rule out
malignancy, avoid futile diagnostic surgeries, and improve patient outcomes in thyroid …

FDG-PET/CT in indeterminate thyroid nodules: cost-utility analysis alongside a randomised controlled trial

EJ de Koster, D Vriens, MO van Aken… - European journal of …, 2022 - Springer
Purpose To evaluate cost-effectiveness of an [18F] FDG-PET/CT-driven diagnostic workup
as compared to diagnostic surgery, for thyroid nodules with Bethesda III/IV cytology.[18F] …

Molecular Diagnostics and [18F]FDG-PET/CT in Indeterminate Thyroid Nodules: Complementing Techniques or Waste of Valuable Resources?

EJ de Koster, H Morreau, GS Bleumink… - Thyroid, 2024 - liebertpub.com
Background: An accurate preoperative workup of cytologically indeterminate thyroid nodules
(ITN) may rule out malignancy and avoid diagnostic surgery for benign nodules. This study …

Quantitative classification and radiomics of [18F]FDG-PET/CT in indeterminate thyroid nodules

EJ de Koster, WA Noortman, JM Mostert, J Booij… - European journal of …, 2022 - Springer
Purpose To evaluate whether quantitative [18F] FDG-PET/CT assessment, including
radiomic analysis of [18F] FDG-positive thyroid nodules, improved the preoperative …

Is 18F-Fluorodeoxyglucose–PET/CT Useful for the Presurgical Characterization of Thyroid Nodules with Indeterminate Fine Needle Aspiration Cytology?

D Deandreis, A Al Ghuzlan, A Auperin, P Vielh… - Thyroid, 2012 - liebertpub.com
Background: Thyroid nodules found incidentally on 18F-fluorodeoxyglucose–positron
emission tomography (FDG-PET) have been shown to be malignant in 30%–50% of cases …

Performance of 18F-FDG PET/CT in Selecting Thyroid Nodules with Indeterminate Fine-Needle Aspiration Cytology for Surgery. A Systematic Review and a Meta …

M Castellana, P Trimboli, A Piccardo… - Journal of clinical …, 2019 - mdpi.com
Thyroid nodules with indeterminate fine-needle aspiration cytology (FNA) represent a major
challenge in clinical practice. We conducted a systematic review and meta-analysis …

18FDG‐positron emission tomography/computed tomography (PET/CT) scanning in thyroid nodules with nondiagnostic cytology

L Giovanella, S Suriano, M Maffioli… - Clinical …, 2011 - Wiley Online Library
Objective To assess the role of positron emission tomography/computed tomography
(PET/CT) scans with 18FDG (18FDG‐PET/CT) in the evaluation of thyroid nodules with …

Could 18F-FDG-PET/CT avoid unnecessary thyroidectomies in patients with cytological diagnosis of follicular neoplasm?

N Munoz Perez, JM Villar del Moral… - … Archives of Surgery, 2013 - Springer
Purpose Preoperative diagnosis of thyroid nodules with “follicular neoplasm”(FN) based on
fine-needle aspiration cytology (FNAC) forces thyroidectomy to exclude malignancy. This …

Exclusion of Malignancy in Thyroid Nodules with Indeterminate Fine‐Needle Aspiration Cytology After Negative 18F‐Fluorodeoxyglucose Positron Emission …

AL Traugott, F Dehdashti, K Trinkaus… - World journal of …, 2010 - Wiley Online Library
Background In all, 20% of fine‐needle aspiration (FNA) biopsies of thyroid nodules have an
indeterminate diagnosis; of these, 80% are found to be benign after thyroidectomy. Some …

18F-FDG PET reduces unnecessary hemithyroidectomies for thyroid nodules with inconclusive cytologic results

LF de Geus-Oei, GFFM Pieters… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Fine-needle aspiration biopsy (FNAB) is inconclusive in up to 20% of patients with solitary
thyroid nodules. In these cases, hemithyroidectomy is necessary, but only 20% of the …