Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies

FM Kashkooli, M Soltani, M Souri - Journal of controlled release, 2020 - Elsevier
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

[HTML][HTML] Smart drug delivery systems for precise cancer therapy

X Wang, C Li, Y Wang, H Chen, X Zhang, C Luo… - … Pharmaceutica Sinica B, 2022 - Elsevier
Nano-drug delivery strategies have been highlighted in cancer treatment, and much effort
has been made in the optimization of bioavailability, biocompatibility, pharmacokinetics …

Recent advances in “smart” delivery systems for extended drug release in cancer therapy

RV Kalaydina, K Bajwa, B Qorri, A Decarlo… - International journal …, 2018 - Taylor & Francis
Advances in nanomedicine have become indispensable for targeted drug delivery, early
detection, and increasingly personalized approaches to cancer treatment. Nanoparticle …

Towards optimal design of cancer nanomedicines: Multi-stage nanoparticles for the treatment of solid tumors

T Stylianopoulos, EA Economides, JW Baish… - Annals of biomedical …, 2015 - Springer
Conventional drug delivery systems for solid tumors are composed of a nano-carrier that
releases its therapeutic load. These two-stage nanoparticles utilize the enhanced …

[HTML][HTML] Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review

S Hossen, MK Hossain, MK Basher, MNH Mia… - Journal of advanced …, 2019 - Elsevier
Nonspecific distribution and uncontrollable release of drugs in conventional drug delivery
systems (CDDSs) have led to the development of smart nanocarrier-based drug delivery …

Stimuli-sensitive nano-drug delivery with programmable size changes to enhance accumulation of therapeutic agents in tumors

M Souri, M Kiani Shahvandi, M Chiani… - Drug Delivery, 2023 - Taylor & Francis
Nano-based drug delivery systems hold significant promise for cancer therapies. Presently,
the poor accumulation of drug-carrying nanoparticles in tumors has limited their success. In …

[HTML][HTML] Nanoplatforms for targeted stimuli-responsive drug delivery: a review of platform materials and stimuli-responsive release and targeting mechanisms

Y Sun, E Davis - Nanomaterials, 2021 - mdpi.com
To achieve the promise of stimuli-responsive drug delivery systems for the treatment of
cancer, they should (1) avoid premature clearance;(2) accumulate in tumors and undergo …

Size-tunable strategies for a tumor targeted drug delivery system

W Yu, R Liu, Y Zhou, H Gao - ACS central science, 2020 - ACS Publications
Nanoparticles have been widely used in tumor targeted drug delivery, while the antitumor
effects are not always satisfactory due to the limited penetration and retention. As we all …

[HTML][HTML] Sustained drug release from smart nanoparticles in cancer therapy: A Comprehensive review

X Bai, ZL Smith, Y Wang, S Butterworth, A Tirella - Micromachines, 2022 - mdpi.com
Although nanomedicine has been highly investigated for cancer treatment over the past
decades, only a few nanomedicines are currently approved and in the market; making this …

Smart targeting to improve cancer therapeutics

M Morales-Cruz, Y Delgado, B Castillo… - Drug design …, 2019 - Taylor & Francis
Cancer is the second largest cause of death worldwide with the number of new cancer
cases predicted to grow significantly in the next decades. Biotechnology and medicine can …