The SARS-CoV-2 pandemic still poses a threat to the global health as the virus continues
spreading in most countries. Therefore, the identification of molecules capable of inhibiting …

All the different coronavirus SARS-CoV-2 variants isolated so far share the same
mechanism of infection mediated by the interaction of their spike (S) glycoprotein with …

DNA aptamers are versatile molecular species obtained by the folding of short single-
stranded nucleotide sequences, with highly specific recognition capabilities against …

We investigated compounds selected by molecular docking to identify a specific treatment
for COVID-19 that decreases the interaction between angiotensin-converting enzyme 2 …

Respiratory transmission is the primary route of Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) infection. Angiotensin I converting enzyme 2 (ACE2) is the …

A universal aptamer against spike-proteins of diverse SARS-CoV-2 variants was discovered
via DNA SELEX towards the wild-type (WT) spike-protein. This aptamer, A1C1, binds to the …

There is increasing evidence that ACE2 gene polymorphism can modulate the interaction
between ACE2 and the SARS-CoV-2 spike protein affecting the viral entry into the host cell …

Aims The COVID-19 disease caused by the SARS-CoV-2 has become a pandemic and
there are no effective treatments that reduce the contagion. It is urgent to propose new …

Respiratory transmission is the primary route of Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) infection. Angiotensin I converting enzyme 2 (ACE2) is the …

The highly infectious disease COVID-19 is induced by SARS-coronavirus 2 (SARS-CoV-2),
which has spread rapidly around the globe and was announced as a pandemic by the World …