Epithelial-mesenchymal transition (EMT) induced by transforming growth factor-β1 (TGF-β1)
is thought to be involved in the pathogenesis of pulmonary fibrosis. Emerging evidence …

Ferroptosis is a new form of regulated cell death. Fibroblast-to-myofibroblast differentiation is
known to be involved in the pathogenesis of idiopathic pulmonary fibrosis. Utilizing HFL1 …

Glutathione peroxidase 4 (Phospholipid hydroperoxide glutathione peroxidase, PHGPx) can
directly reduce phospholipid hydroperoxide. Depletion of GPx4 induces lipid peroxidation …

Ferroptosis can be induced by inhibiting antioxidant enzymes GPX4 or system Xc−,
increased intracellular iron concentrations, and lipid peroxidation. Recently, it has been …

Ferroptosis is a newly discovered type of regulated cell death, characterized by the iron-
dependent accumulation of lipid reactive oxygen species, which has been implicated in …

Background. Lung fibrosis is a severe lung disorder featured by chronic nonspecific
inflammation of the interstitial lung and deposition of collagen, leading to lung dysfunction. It …

Aims Ferroptosis is involved in the pathogenesis of spinal cord injury (SCI). Carnosic acid
(CA) is a natural phenolic diterpene, which possesses diversiform activities. However …

Ferroptosis is a distinct type of programmed cell death (PCD) that depends on iron and is
characterized by the accumulation of intracellular iron, exhaustion of glutathione …

Introduction β-Elemene (β-ELE), derived from Curcuma wenyujin, has anticancer effect on
non-small cell lung cancer (NSCLC). However, the potential target and detail mechanism …

Ferroptosis is a new form of programmed cell death due to iron-dependent excess
accumulation of lipid peroxides and differs from other programmed cell deaths in …