Reconciling the distinct roles of angiogenic/anti-angiogenic factors in the placenta and maternal circulation of normal and pathological pregnancies

A Umapathy, LW Chamley, JL James - Angiogenesis, 2020 - Springer
A branched vascular network is crucial to placental development and is dependent on
factors such as vascular endothelial growth factor (VEGF), placental growth factor (PlGF) …

[HTML][HTML] Regulation of vascular growth and function in the human placenta

GJ Burton, DS Charnock-Jones, E Jauniaux - Reproduction, 2009 - rep.bioscientifica.com
During the course of 9 months, the human placenta develops into a highly vascular organ.
Vasculogenesis starts during the third week post-conception. Hemangioblastic cell cords …

Regulation of placental angiogenesis

D Chen, J Zheng - Microcirculation, 2014 - Wiley Online Library
Ample interest has been evoked in using placental angiogenesis as a target for the
development of diagnosis tools and potential therapeutics for pregnancy complications …

Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth …

E Geva, DG Ginzinger, CJ Zaloudek… - The Journal of …, 2002 - academic.oup.com
During placental development, vessel formation occurs initially by vasculogenesis and
subsequently by branching and nonbranching angiogenesis. We investigated vascular …

Update on the pathophysiological implications and clinical role of angiogenic factors in pregnancy

E Llurba, F Crispi, S Verlohren - Fetal diagnosis and therapy, 2015 - karger.com
Angiogenic markers are now being incorporated into clinical practice for the screening,
diagnosing, and monitoring of preeclampsia. Pregnancy requires both vasculogenesis and …

Angiogenic factors in preeclampsia and related disorders

AS Cerdeira, SA Karumanchi - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
During fetal development, the human placenta undergoes high levels of both angiogenesis
and vasculogenesis. Additionally, the developing placenta undergoes a process of vascular …

Disrupted balance of angiogenic and antiangiogenic signalings in preeclampsia

M Furuya, K Kurasawa, K Nagahama… - Journal of …, 2011 - Wiley Online Library
The placenta plays a central role in governing local circulatory system that mediates
maternal condition and fetal growth. In early gestational phases, the placenta exerts …

Angiogenesis and vasculogenesis in pregnancy

M Zygmunt, F Herr, K Münstedt, U Lang… - European Journal of …, 2003 - Elsevier
An adequate nutrient and substrate supply is essential for normal intrauterine development
of the fetus. Disturbances in uterine blood supply are associated with higher perinatal …

Angiogenic factors in placentas from pregnancies complicated by fetal growth restriction

V Gourvas, E Dalpa… - Molecular …, 2012 - spandidos-publications.com
The placenta is the organ that is responsible for providing the developing fetus with all the
nutrients necessary for its growth and is also responsible for removing fetal waste …

Establishment of the human uteroplacental circulation: a historical perspective

K Degner, RR Magness, DM Shah - Reproductive sciences, 2017 - journals.sagepub.com
The uterine vasculature undergoes marked changes during pregnancy in order to provide
the necessary increase in blood flow to support growth and nutrition of the uterus, placenta …