Obesity exerts negative effects on the metabolic homeostasis of cells in various tissues, but
how it influences ovum metabolism is not fully understood. Previous studies demonstrate …

Although obesity negatively influences the metabolic homeostasis of cells within a broad
range of tissues, its impact on oocyte metabolism is not fully understood. Prior evidence …

Well-balanced metabolism is essential for the high-quality of oocytes, and metabolic
fluctuations of follicular microenvironment potentially encourage functional changes in …

STUDY QUESTION What metabolic pathways and metabolites in the serum and follicular
fluid are associated with peak estradiol levels and the number of mature oocytes …

Background Follicular fluid is an important external environment for the growth and
development of oocytes. A thorough identification of specific components in follicular fluid …

Infertility is a worldwide concern, affecting one in six couples throughout their reproductive
period. Therefore, enhancing the clinical tools available to identify the causes of infertility …

In order to investigate the metabolic characteristics of human follicular fluid (FF) and to
reveal potential metabolic predictors of follicular development (FD) with clinical implications …

Female fertility declines with age, and this natural variation culminates in reproductive
senescence. Human follicular fluids are rich in low-molecular weight metabolites which are …

Introduction: Obesity is an epidemic affecting more than one-third of adults in the United
States. Obese women experience decreased fertility, explained in part by oocyte quality …

Context. Polycystic ovary syndrome (PCOS) is a gynecological endocrine disease, and
approximately 60% of patients with PCOS have different degrees of insulin resistance (IR) …