Using epigenetic clocks to characterize biological aging in studies of children and childhood exposures: A systematic review
RJ Musci, RS Raghunathan, SB Johnson, L Klein… - Prevention …, 2023 - Springer
Biological age, measured via epigenetic clocks, offers a unique and useful tool for
prevention scientists to explore the short-and long-term implications of age deviations for …
prevention scientists to explore the short-and long-term implications of age deviations for …
[HTML][HTML] A systematic review of biological, social and environmental factors associated with epigenetic clock acceleration
L Oblak, J van der Zaag, AT Higgins-Chen… - Ageing research …, 2021 - Elsevier
Aging involves a diverse set of biological changes accumulating over time that leads to
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …
Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children
Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …
turn has been shown to predict numerous physical and mental health problems. In recent …
Assessment of epigenetic clocks as biomarkers of aging in basic and population research
ME Levine - The Journals of Gerontology: Series A, 2020 - academic.oup.com
The Geoscience paradigm suggests that targeting the aging process could delay or prevent
the risk of multiple major age-related diseases, such as cancer, cardiovascular disease …
the risk of multiple major age-related diseases, such as cancer, cardiovascular disease …
Epigenetic clocks and research implications of the lack of data on whom they have been developed: a review of reported and missing sociodemographic …
Epigenetic clocks are increasingly being used as a tool to assess the impact of a wide
variety of phenotypes and exposures on healthy ageing, with a recent focus on social …
variety of phenotypes and exposures on healthy ageing, with a recent focus on social …
Statistical and conceptual considerations in socioepigenomics research on childhood adversity and epigenetic aging
Applications of epigenetic clocks to health questions have proliferated over the past decade,
particularly as a means of understanding disease etiology. Epigenetic clocks are aggregate …
particularly as a means of understanding disease etiology. Epigenetic clocks are aggregate …
Epigenetic clocks in the pediatric population: when and why they tick?
J Wang, WH Zhou - Chinese Medical Journal, 2021 - mednexus.org
Recent research efforts have provided compelling evidence of genome-wide DNA
methylation alterations in pediatrics. It is currently well established that epigenetic clocks …
methylation alterations in pediatrics. It is currently well established that epigenetic clocks …
Epigenetic clock: A promising biomarker and practical tool in aging
R Duan, Q Fu, Y Sun, Q Li - Ageing Research Reviews, 2022 - Elsevier
As a complicated process, aging is characterized by various changes at the cellular,
subcellular and nuclear levels, one of which is epigenetic aging. With increasing awareness …
subcellular and nuclear levels, one of which is epigenetic aging. With increasing awareness …
R methylCIPHER: a methylation clock investigational package for hypothesis-driven evaluation & research
Background Epigenetic clocks are promising tools for the study of aging in humans. The
clocks quantify biological aging above and beyond chronological age, demonstrate …
clocks quantify biological aging above and beyond chronological age, demonstrate …
“Epigenetic clocks”: Theory and applications in human biology
CP Ryan - American Journal of Human Biology, 2021 - Wiley Online Library
All humans age, but how we age—and how fast—differs considerably from person to
person. This deviation between apparent age and chronological age is often referred to as …
person. This deviation between apparent age and chronological age is often referred to as …
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