Methods: We synthesized randomized controlled studies (RCTs) from the Web of Science,
SCOPUS, EMBASE, PubMed, and CENTRAL until 13 October 2022. The risk ratio (RR) for …

Blood pressure (BP) fluctuates over 24 h, and the sympathomimetic autonomic nervous
system drives these circadian variations due to increased activity of renin-angiotensin …

Introduction Studies have suggested that different administration times may lead to different
antihypertensive effects. This systematic review was designed to evaluate the effectiveness …

Antihypertensive drug therapy is one of the most efficient medical interventions for
preventing disability and death globally. Most of the evidence supporting its benefits has …

Background: The timing of antihypertensive drugs administration is controversial. The aim
was to compare the efficacy of dosing of antihypertensive drugs in the morning versus …

Nighttime blood pressure strongly predicts cardiovascular events (CVE s). Further, a
preliminary trial has shown decreased CVE s from evening vs morning dosing of …

Background: It is well known that morning blood pressure surge increases the risk of
myocardial events in the first several hours post-awakening. This meta-analysis was …

Should blood pressure (BP) medications be taken in the morning or in the evening? The
TIME study results were presented at the ESC congress 2022 and published not too long …

Background Studies have suggested that evening dosing with antihypertensive therapy
might have better outcomes than morning dosing. The Treatment in Morning versus Evening …

Background Variation in blood pressure levels display circadian rhythms. The morning
surge in blood pressure is known to increase the risk of myocardial events in the first several …