[HTML][HTML] Regulating trained immunity with nanomedicine

MMT van Leent, B Priem, DP Schrijver… - Nature Reviews …, 2022 - nature.com
Trained immunity refers to a hyperresponsive functional state of the innate immune system,
which is induced by certain stimuli, such as infections or vaccination. Trained immunity plays …

Enhancing immunity with nanomedicine: employing nanoparticles to harness the immune system

CT Perciani, LY Liu, L Wood, SA MacParland - ACS nano, 2020 - ACS Publications
The failure of immune responses to vaccines and dysfunctional immune responses to viral
infection, tumor development, or neoantigens lead to chronic viral infection, tumor …

Nanoparticles for immune stimulation against infection, cancer, and autoimmunity

S Singha, K Shao, KK Ellestad, Y Yang, P Santamaria - ACS nano, 2018 - ACS Publications
Vaccination using nanocarrier-based delivery systems has recently emerged as a promising
approach for meeting the continued challenge posed by infectious diseases and cancer. A …

Immunomodulatory nanosystems

X Feng, W Xu, Z Li, W Song, J Ding… - Advanced science, 2019 - Wiley Online Library
Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …

Nanoparticle-based modulation of the immune system

RH Fang, L Zhang - Annual Review of Chemical and …, 2016 - annualreviews.org
The immune system is an incredibly complex biological network that plays a significant role
in almost all disease pathogenesis. With an increased understanding of how this vital …

[HTML][HTML] Nano toolbox in immune modulation and nanovaccines

M Azharuddin, GH Zhu, A Sengupta, J Hinkula… - Trends in …, 2022 - cell.com
Despite the great success of vaccines over two centuries, the conventional strategy is based
on attenuated/altered microorganisms. However, this is not effective for all microbes and …

Modulating the immune system through nanotechnology

TG Dacoba, A Olivera, D Torres… - Seminars in …, 2017 - Elsevier
Nowadays, nanotechnology-based modulation of the immune system is presented as a
cutting-edge strategy, which may lead to significant improvements in the treatment of severe …

[HTML][HTML] Innate and adaptive immune responses toward nanomedicines

IM de Oliveira Viana, S Roussel, J Defrêne… - … Pharmaceutica Sinica B, 2021 - Elsevier
Since the commercialization of the first liposomes used for drug delivery, Doxil/Caelyx® and
Myocet®, tremendous progress has been made in understanding interactions between …

[HTML][HTML] Biomedical nanomaterials for immunological applications: ongoing research and clinical trials

V Lenders, X Koutsoumpou, A Sargsian… - Nanoscale …, 2020 - pubs.rsc.org
Research efforts on nanomaterial-based therapies for the treatment of autoimmune diseases
and cancer have spiked and have made rapid progress over the past years. Nanomedicine …

Synthetic nanovaccines for immunotherapy

M Luo, LZ Samandi, Z Wang, ZJ Chen, J Gao - Journal of controlled release, 2017 - Elsevier
Although vaccination is historically one of the most successful strategies for the prevention of
infectious diseases, development of vaccines for cancer and many chronic infections, such …