Mesenchymal stem-cell-derived small extracellular vesicles (MSC-EVs), as a therapeutic
agent, have shown great promise in the treatment of neurological diseases. To date, the …

Background: Mesenchymal stem cells (MSCs)-derived extracellular vesicles (EVs) have
been reported to exhibit therapeutic effects in various animal models of neurological …

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive loss
of neurons in the brain. However, there are no effective drugs for AD. Mesenchymal stem …

Bone marrow Mesenchymal Stem Cells (BM-MSCs), due to their strong protective and anti-
inflammatory abilities, have been widely investigated in the context of several diseases for …

Herein, we investigate the bioactivity of small extracellular vesicles (sEVs), focusing on their
local effect in the brain. sEVs from mononuclear cells (MNCs) showed superior effects in …

Alzheimer's disease (AD), as a neurodegenerative disorder, is characterized by mass
neuronal and synaptic loss and, currently, there are no successful curative therapies …

AlzheimerLs disease (AD) is the most common neurodegenerative disorder and the No. 1
cause of dementia in elderly with no effective treatments. 1 The application of stem cell …

Currently, Alzheimer's disease (AD) cannot be treated effectively. Mesenchymal stem cells
(MSCs)-derived extracellular vesicles (EVs)(MSC-EVs) exhibit therapeutic effects on many …

No cure yet exists for devastating Alzheimer's disease (AD), despite many years and
humongous efforts to find efficacious pharmacological treatments. So far, neither designing …