Engineering Y. lipolytica for the biosynthesis of geraniol

A Agrawal, Z Yang, M Blenner - bioRxiv, 2023 - biorxiv.org
Geraniol is a monoterpene with wide applications in the food, cosmetics, and
pharmaceutical industries. Microbial production has largely used model organisms lacking …

[HTML][HTML] Engineering Yarrowia lipolytica for the biosynthesis of geraniol

A Agrawal, Z Yang, M Blenner - Metabolic Engineering Communications, 2023 - Elsevier
Geraniol is a monoterpene with wide applications in the food, cosmetics, and
pharmaceutical industries. Microbial production has largely used model organisms lacking …

[HTML][HTML] Yarrowia lipolytica Strains Engineered for the Production of Terpenoids

JA Arnesen, KR Kildegaard… - … in Bioengineering and …, 2020 - frontiersin.org
Terpenoids are a diverse group of over 55,000 compounds with potential applications as
advanced fuels, bulk and fine chemicals, pharmaceutical ingredients, agricultural chemicals …

Microaerobic Fermentation Enables High-Titer Biosynthesis of the Rose Monoterpenes Geraniol and Geranyl Acetate in Escherichia coli

S Shukal, L Ong, X Chen, C Zhang - ACS Sustainable Chemistry …, 2024 - ACS Publications
Monoterpenes are commercially important flavors and fragrances with high demand.
Microbial production of monoterpenes is more sustainable than plant extraction, however, it …

Engineering Escherichia coli for production of geraniol by systematic synthetic biology approaches and laboratory-evolved fusion tags

X Wang, J Chen, J Zhang, Y Zhou, Y Zhang… - Metabolic …, 2021 - Elsevier
Geraniol is a valuable monoterpene extensively used in the fragrance, food, and cosmetic
industries. Increasing environmental concerns and supply gaps have motivated efforts to …

Transcriptome analysis and targeted metabolic profiling for pathway elucidation and identification of a geraniol synthase involved in iridoid biosynthesis from Gardenia …

P Ye, S Liang, X Wang, L Duan, F Jiang-Yan… - Industrial Crops and …, 2019 - Elsevier
Iridoid compounds have been reported to be accumulated in the dried fruits of Gardenia
jasminoides (Rubiaceae), which are used in traditional Chinese medicine. These …

An enzyme-coupled assay enables rapid protein engineering for geraniol production in yeast

JL Lin, H Ekas, K Markham, HS Alper - Biochemical Engineering Journal, 2018 - Elsevier
Geraniol is an important monoterpene alcohol with various industrial applications. The
biological synthesis of geraniol requires the activity of geraniol synthase (GES). Despite …

Advances in terpenes biosynthesis by Yarrowia lipolytica: subtle but effective engineering strategies.

LIU Qi, DAI Zongjie, W Qinhong - Chinese Journal of …, 2022 - search.ebscohost.com
Terpenes are natural compounds based on C5 unit isoprene, with a variety of biological
activities and are widely used in food, pharmaceutical and chemical industries. Traditionally …

[HTML][HTML] Dynamic control of ERG20 expression combined with minimized endogenous downstream metabolism contributes to the improvement of geraniol production …

J Zhao, C Li, Y Zhang, Y Shen, J Hou, X Bao - Microbial cell factories, 2017 - Springer
Background Microbial production of monoterpenes provides a promising substitute for
traditional chemical-based methods, but their production is lagging compared with …

[HTML][HTML] Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture

W Liu, X Xu, R Zhang, T Cheng, Y Cao, X Li… - Biotechnology for …, 2016 - Springer
Background Geraniol is an acyclic monoterpene alcohol, which exhibits good prospect as a
gasoline alternative. Geraniol is naturally encountered in plants at low concentrations and …