[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation

DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Piwi-interacting RNAs (piRNAs) are a class of short chain noncoding RNAs that are
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …

The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers

Q Zhang, Y Zhu, X Cao, W Tan, J Yu, Y Lu, R Kang… - Molecular Cancer, 2023 - Springer
PIWI proteins have a strong correlation with PIWI-interacting RNAs (piRNAs), which are
significant in development and reproduction of organisms. Recently, emerging evidences …

The biogenesis and functions of piRNAs in human diseases

X Wu, Y Pan, Y Fang, J Zhang, M Xie, F Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
Piwi-interacting RNAs (piRNAs) are a novel type of small noncoding RNAs, which are 26–30
nt in length and bind to Piwi proteins. These short RNAs were originally discovered in …

The emerging role of the piRNA/piwi complex in cancer

Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …

Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases

Z Wu, X Yu, S Zhang, Y He, W Guo - Cell Communication and Signaling, 2023 - Springer
Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …

Role of PIWI‐interacting RNAS on cell survival: Proliferation, apoptosis, and cycle

Q Zeng, H Wan, S Zhao, H Xu, T Tang, KA Oware… - IUBMB …, 2020 - Wiley Online Library
PIWI‐interacting RNAs (piRNAs) are a kind of non‐coding small RNAs, which play a
biological role by specifically binding to PIWI proteins. Studies have demonstrated that …

[HTML][HTML] Emerging roles of piRNAs in cancer: challenges and prospects

YE Cheng, Q Wang, W Jiang, Y Bian, A Gou… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
PiRNAs are a small class of non-coding small RNAs newly discovered in recent years.
Millions of piRNAs have been discovered to date, and more than 20,000 piRNA genes have …

Novel dimensions of piRNAs in cancer

Y Mei, D Clark, L Mao - Cancer letters, 2013 - Elsevier
Piwi-interacting RNAs (piRNAs), a newly identified class of small non-coding RNAs, direct
the Piwi-dependent transposon silencing, heterochromatin modification and germ cell …

Overexpression of piRNA pathway genes in epithelial ovarian cancer

SL Lim, C Ricciardelli, MK Oehler, IMD De Arao Tan… - PloS one, 2014 - journals.plos.org
The importance of the Piwi-interacting RNA (piRNA) pathway for germ cell maintenance,
genome integrity, DNA methylation and retrotransposon control raises possible roles of this …

Emerging functions of piwi‐interacting RNAs in diseases

K Wang, T Wang, XQ Gao, XZ Chen… - Journal of cellular …, 2021 - Wiley Online Library
PIWI‐interacting RNAs (piRNAs) are recently discovered small non‐coding RNAs consisting
of 24‐35 nucleotides, usually including a characteristic 5‐terminal uridine and an adenosine …