Background Individuals born very low birthweight (VLBW) are at increased risk of impaired
cardiovascular and respiratory function in adulthood. To identify markers to predict future risk …

Background Globally, one in ten babies is born preterm (< 37 weeks), and 1–2% preterm at
very low birth weight (VLBW,< 1500 g). As adults, they are at increased risk for a plethora of …

Background Infants being born Large-for-gestational-age (LGA) are prone to developing
cardiometabolic disease. However, the underlying mechanisms remain unclear. Results …

Background Infants born very preterm are more likely to experience neonatal morbidities
compared to their term peers. Variations in DNA methylation (DNAm) associated with these …

Birthweight is associated with health outcomes across the life course, DNA methylation may
be an underlying mechanism. In this meta-analysis of epigenome-wide association studies …

Background Prenatal risk factors are related to poor health and developmental outcomes for
infants, potentially via epigenetic mechanisms. We tested associations between person …

Pregnancy is a valuable model to study the association between DNA methylation and
several cardiometabolic traits, due to its direct potential to influence mother's and child's …

Many epidemiological studies have linked low birthweight to an increased risk of non-
communicable diseases (NCDs) in later life, with epigenetic proceseses suggested as an …

Abstract Background In 1990, David Barker proposed that prenatal nutrition is directly linked
to adult cardiovascular disease. Since then, the relationship between adult cardiovascular …

There is great interest in the role epigenetic variation induced by non-genetic exposures
may play in the context of health and disease. In particular, DNA methylation has previously …