Nearly all cell surface receptors utilize one or more of the mitogen-activated protein kinase
cascades in their repertoire of signal transduction mechanisms. Recent advances in the …

Mitogen-activated protein (MAP) kinases are proline-directed serine/threonine protein
kinases that are activated via phosphorylation of their own tyrosine residues. Highly …

An explosion of new information linking activation of cell surface signal initiators to changes
in gene expression has recently emerged. The focus of much of this information has …

The covalent modification of cellular proteins by phosphorylation is a prominent feature of
pathways by which the cell-surface receptors of eukaryotes transduce extracellular signals …

Mitogen-activated protein (MAP)'kinases are important intermediates in signal transduction
pathways that are initiated by many types of cell surface receptors. The final common …

Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen-
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …

Mitogen-activated protein kinases (MAPKs) are components of a three kinase regulatory
cascade. There are multiple members of each component family of kinases in the MAPK …

A number of different intracellular signaling pathways have been shown to be activated by
receptor tyrosine kinases. These activation events include the phosphoinositide 3-kinase, 70 …

Much attention has recently been focused on the role played by kinases of the mitogen
activated protein kinase (MAPK) family in signal transduction 1, 2. MAPK is, however, onl) …

Activation of the mitogen activated protein kinase (MAPK) plays esential roles in many signal
transduction pathways. MAPK has been demonstrated to phosphorylate and regulate …