[HTML][HTML] Biodegradable Zn–Sr alloy for bone regeneration in rat femoral condyle defect model: In vitro and in vivo studies

B Jia, H Yang, Z Zhang, X Qu, X Jia, Q Wu, Y Han… - Bioactive materials, 2021 - Elsevier
Bone defects are commonly caused by severe trauma, malignant tumors, or congenital
diseases and remain among the toughest clinical problems faced by orthopedic surgeons …

In vitro and in vivo studies of Zn-Mn biodegradable metals designed for orthopedic applications

B Jia, H Yang, Y Han, Z Zhang, X Qu, Y Zhuang, Q Wu… - Acta Biomaterialia, 2020 - Elsevier
In recent years, Zn-based materials provide a new option as biodegradable metals for
orthopedic applications. To improve the low strength and brittle nature of pure Zn, small …

Zinc-based biomaterials for bone repair and regeneration: mechanism and applications

X Wen, J Wang, X Pei, X Zhang - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Zinc (Zn) is one of the most important trace elements in the human body and plays a key role
in various physiological processes, especially in bone metabolism. Zn-containing materials …

[HTML][HTML] Biodegradable ZnLiCa ternary alloys for critical-sized bone defect regeneration at load-bearing sites: In vitro and in vivo studies

Z Zhang, B Jia, H Yang, Y Han, Q Wu, K Dai, Y Zheng - Bioactive Materials, 2021 - Elsevier
A novel biodegradable metal system, ZnLiCa ternary alloys, were systematically
investigated both in vitro and in vivo. The ultimate tensile strength (UTS) of Zn0. 8Li0. 1Ca …

Microstructure, mechanical properties, biocompatibility, and in vitro corrosion and degradation behavior of a new Zn–5Ge alloy for biodegradable implant materials

X Tong, D Zhang, X Zhang, Y Su, Z Shi, K Wang, J Lin… - Acta biomaterialia, 2018 - Elsevier
Zinc (Zn)-based alloys are considered a new class of biodegradable implant materials due
to their superior chemical stability and processability compared to biodegradable …

[HTML][HTML] Systematic in vitro and in vivo study on biodegradable binary Zn-0.2 at% Rare Earth alloys (Zn-RE: Sc, Y, La–Nd, Sm–Lu)

S Du, Y Shen, Y Zheng, Y Cheng, X Xu, D Chen… - Bioactive Materials, 2023 - Elsevier
Biomedical implants and devices for tissue engineering in clinics, mainly made of polymers
and stiff metallic materials, require possibly secondary surgery or life-long medicine …

Biodegradable Zn–Dy binary alloys with high strength, ductility, cytocompatibility, and antibacterial ability for bone-implant applications

X Tong, Y Han, R Zhou, W Jiang, L Zhu, Y Li, S Huang… - Acta Biomaterialia, 2023 - Elsevier
The unique combination of biodegradability, biocompatibility, and functionality of zinc (Zn)-
based alloys makes them highly desirable for a wide range of medical applications …

Indirectly extruded biodegradable Zn-0.05 wt% Mg alloy with improved strength and ductility: In vitro and in vivo studies

C Xiao, L Wang, Y Ren, S Sun, E Zhang, C Yan… - Journal of materials …, 2018 - Elsevier
As compared to permanent orthopedic implants for load-bearing applications,
biodegradable orthopedic implants have the advantage of no need for removing after …

[HTML][HTML] Investigation of zinc-silver alloys as biodegradable metals for orthopedic applications

X Xiao, B Wang, E Liu, H Liu, L Liu, W Xu, S Ge… - Journal of Materials …, 2023 - Elsevier
Biodegradable zinc (Zn) alloys are promising implant materials to restore bone defects in
orthopedics. Adding silver (Ag) to Zn not only enhances its mechanical properties but also …

A biomimetic zinc alloy scaffold coated with brushite for enhanced cranial bone regeneration

Y Zhuang, Q Liu, G Jia, H Li, G Yuan… - … Biomaterials Science & …, 2020 - ACS Publications
Bone tissue engineering is considered as a promising pathway for bone regeneration and
defect reconstruction, in which scaffolds play an important role. Zn alloy, which is a …