Developmental programming by maternal obesity in 2015: Outcomes, mechanisms, and potential interventions

NC Penfold, SE Ozanne - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “SBN 2014”. Obesity in women of child-bearing age is a
growing problem in developed and developing countries. Evidence from human studies …

Developmental programming by maternal obesity: Lessons from animal models

JM Schoonejans, SE Ozanne - Diabetic Medicine, 2021 - Wiley Online Library
The obesity epidemic has led to more women entering pregnancy overweight or obese. In
addition to adverse short‐term outcomes, maternal obesity and/or gestational diabetes …

Developmental programming in response to maternal overnutrition

MZ Alfaradhi, SE Ozanne - Frontiers in genetics, 2011 - frontiersin.org
Metabolic disorders have seen an increased prevalence in recent years in developed as
well as developing countries. While it is clear lifestyle choices and habits have contributed to …

Maternal obesity: lifelong metabolic outcomes for offspring from poor developmental trajectories during the perinatal period

E Zambrano, C Ibáñez, PM Martinez-Samayoa… - Archives of medical …, 2016 - Elsevier
The prevalence of obesity in women of reproductive age is increasing in developed and
developing countries around the world. Human and animal studies indicate that maternal …

Persistent influence of maternal obesity on offspring health: Mechanisms from animal models and clinical studies

UD Wankhade, KM Thakali, K Shankar - Molecular and cellular …, 2016 - Elsevier
The consequences of excessive maternal weight and adiposity at conception for the
offspring are now well recognized. Maternal obesity increases the risk of overweight and …

Mechanisms mediating the impact of maternal obesity on offspring hypothalamic development and later function

IC Furigo, L Dearden - Frontiers in endocrinology, 2022 - frontiersin.org
As obesity rates have risen around the world, so to have pregnancies complicated by
maternal obesity. Obesity during pregnancy is not only associated with negative health …

Effects of neonatal programming on hypothalamic mechanisms controlling energy balance

C Contreras, MG Novelle, R Leis… - Hormone and …, 2013 - thieme-connect.com
The prevalence of overweight and obesity in most developed countries has markedly
increased during the last decades. In addition to genetic, hormonal, and metabolic …

Early life programming of health and disease: The long‐term consequences of obesity in pregnancy

SC Langley‐Evans - Journal of Human Nutrition and Dietetics, 2022 - Wiley Online Library
The prevalence of overweight and obesity is rising in all parts of the world and, among
young women, it presents a very clear danger during pregnancy. Women who are …

The Endocrine–Metabolic Axis Regulation in Offspring Exposed to Maternal Obesity—Cause or Consequence in Metabolic Disease Programming?

LF Grilo, MS Diniz, C Tocantins, AL Areia, SP Pereira - Obesities, 2022 - mdpi.com
Obesity incidence is rising worldwide, including women of reproductive age, contributing to
increased gestations in which Maternal Obesity (MO) occurs. Offspring born to obese …

Early life influences on obesity risk: maternal overnutrition and programming of obesity

MJ Morris - Expert Review of Endocrinology & Metabolism, 2009 - Taylor & Francis
While adult lifestyle factors undoubtedly contribute to the incidence of obesity and its
attendant disorders, mounting evidence suggests that programming of obesity may occur …