[HTML][HTML] Is fat the future for saving sight? Bioactive lipids and their impact on glaucoma
M Kolko, ZA Mouhammad, B Cvenkel - Pharmacology & Therapeutics, 2023 - Elsevier
Glaucoma is characterized by a continuous loss of retinal ganglion cells. The cause of
glaucoma is associated with an increase in intraocular pressure (IOP), but the underlying …
glaucoma is associated with an increase in intraocular pressure (IOP), but the underlying …
Endogenous ocular lipids as potential modulators of intraocular pressure
G Edwards, J Arcuri, H Wang, N Ziebarth… - Journal of cellular …, 2020 - Wiley Online Library
Elevated intraocular pressure (IOP) is a risk factor in glaucoma, a group of irreversible
blinding diseases. Endogenous lipids may be involved in regulation of IOP homeostasis. We …
blinding diseases. Endogenous lipids may be involved in regulation of IOP homeostasis. We …
Targeted Lipidomic analysis of aqueous humor reveals signaling lipid-mediated pathways in primary open-angle Glaucoma
Simple Summary Analysis of the eye liquids collected from a cohort of primary open-angle
glaucoma patients identified signaling lipids, the pattern of which suggests a role of …
glaucoma patients identified signaling lipids, the pattern of which suggests a role of …
Lipid signaling in ocular neovascularization
R Terao, H Kaneko - International journal of molecular sciences, 2020 - mdpi.com
Vasculogenesis and angiogenesis play a crucial role in embryonic development.
Pathological neovascularization in ocular tissues can lead to vision-threatening vascular …
Pathological neovascularization in ocular tissues can lead to vision-threatening vascular …
The role of lipids in corneal diseases and dystrophies: a systematic review
TG Rowsey, D Karamichos - Clinical and translational medicine, 2017 - Springer
Corneal diseases are an extensive cause of blindness worldwide and continue to persist as
a challenging public health concern. Recently, various lipid-based therapies have been …
a challenging public health concern. Recently, various lipid-based therapies have been …
[HTML][HTML] A meta-analysis of glaucoma risk in hyperlipidemic individuals: a critical problem in design
IC Hwang, YJ Lee, JH Bae - Investigative Ophthalmology & …, 2016 - jov.arvojournals.org
Because glaucoma is the leading cause of irreversible visual impairment and is usually
undetectable until advanced stages, 1 investigations on modifiable factors associated with …
undetectable until advanced stages, 1 investigations on modifiable factors associated with …
Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma
PV Rao - Journal of ocular pharmacology and therapeutics, 2014 - liebertpub.com
Homeostasis of aqueous humor (AH) outflow and intraocular pressure (IOP) is essential for
normal vision. Impaired AH outflow through the trabecular meshwork (TM) and a resultant …
normal vision. Impaired AH outflow through the trabecular meshwork (TM) and a resultant …
Ocular treatments targeting separate prostaglandin receptors in mice exhibit alterations in intraocular pressure and optic nerve lipidome
J Arcuri, A Elbaz, NA Sharif… - Journal of Ocular …, 2023 - liebertpub.com
Background: Prostaglandin (PG) receptor agonists are the first-line eyedrop medication
treatment for glaucoma. The pathophysiology of this disease is not completely known, and …
treatment for glaucoma. The pathophysiology of this disease is not completely known, and …
[HTML][HTML] Hyperlipidemia, blood lipid level, and the risk of glaucoma: a meta-analysis
S Wang, X Bao - Investigative ophthalmology & visual science, 2019 - tvst.arvojournals.org
Purpose: Previous studies reported that hyperlipidemia and blood lipid levels were
associated with glaucoma, ocular hypertension (OHT), and intraocular pressure (IOP) …
associated with glaucoma, ocular hypertension (OHT), and intraocular pressure (IOP) …
Introduction to the thematic review series: seeing 2020: lipids and lipid-soluble molecules in the eye
SJ Fliesler - Journal of lipid research, 2021 - ASBMB
In 2010, this journal published a series of review articles in a Thematic Issue entitled “Lipids
and Lipid Metabolism in the Eye.” Over the ensuing decade, a number of significant …
and Lipid Metabolism in the Eye.” Over the ensuing decade, a number of significant …