Functional proteomic investigation of extracellular vesicles: Rai+/+ vs Rai-/-astrocytes and released vesicles in EAE and bronchoalveolar lavage fluid-extracted …

E Shaba - 2021 - usiena-air.unisi.it
In the recent years, extracellular vesicles (EVs) drew a growing interest in scientific
community, especially for their intrinsic role of cell-cell communication entities between local …

Proteome characterization of BALF extracellular vesicles in idiopathic pulmonary fibrosis: Unveiling undercover molecular pathways

E Shaba, C Landi, A Carleo, L Vantaggiato… - International Journal of …, 2021 - mdpi.com
In the longtime challenge of identifying specific, easily detectable and reliable biomarkers of
IPF, BALF proteomics is providing interesting new insights into its pathogenesis. To the best …

[HTML][HTML] Proteomic analysis reveals key proteins in extracellular vesicles cargo associated with idiopathic pulmonary fibrosis in vitro

JM Velázquez-Enríquez, JC Santos-Álvarez… - Biomedicines, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, and highly fatal
disease. It is characterized by the increased activation of both fibroblast and myofibroblast …

A novel protein signature from plasma extracellular vesicles for non-invasive differential diagnosis of idiopathic pulmonary fibrosis

RSR Adduri, K Cai, KV Alzate, R Vasireddy, JW Miller… - medRxiv, 2021 - medrxiv.org
Background Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial pneumonia of
unknown etiology often leading to respiratory failure. Over half of IPF patients present with …

Plasma extracellular vesicle proteins as promising noninvasive biomarkers for diagnosis of idiopathic pulmonary fibrosis

RSR Adduri, K Cai, K Velasco‐Alzate… - Journal of …, 2023 - Wiley Online Library
High‐resolution computed tomography (HRCT) imaging is critical for diagnostic evaluation
of Idiopathic Pulmonary Fibrosis (IPF). However, several other interstitial lung diseases …

Proteomics of blood extracellular vesicles in inflammatory respiratory diseases for biomarker discovery and new insights into pathophysiology

T Kawasaki, Y Takeda, A Kumanogoh - Inflammation and Regeneration, 2024 - Springer
Background Inflammatory respiratory diseases, such as interstitial lung disease (ILD),
bronchial asthma (BA), chronic obstructive pulmonary disease (COPD), and respiratory …

Fibroblasts-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis

O Burgy, CH Mayr, BB Llobell, A Sengupta… - bioRxiv, 2022 - biorxiv.org
Idiopathic pulmonary fibrosis (IPF) is a lethal and chronic lung disease characterized by
aberrant intercellular communication, increased extracellular matrix (ECM) deposition, and …

The effects of interstitial lung diseases on alveolar extracellular vesicles profile: A multicenter study

M d'Alessandro, S Gangi, P Soccio, E Cantó… - International Journal of …, 2023 - mdpi.com
Diagnosis of interstitial lung diseases (ILD) is difficult to perform. Extracellular vesicles (EVs)
facilitate cell-to-cell communication, and they are released by a variety of cells. Our goal …

Extracellular vesicles in pulmonary fibrosis models and biological fluids of interstitial lung disease patients: A scoping review

M d'Alessandro, L Bergantini, E Bargagli, S Vidal - Life, 2021 - mdpi.com
Introduction: Interstitial lung diseases (ILDs) are a heterogeneous group of diffuse
parenchymal lung disorders characterized by the pathogenetic involvement of interstitium …

A multicenter study of extracellular vesicles profile in bronchoalveolar lavage from patients affected by IPF, HP and sarcoidosis

M d'Alessandro, S Gangi, P Soccio, E Cantó, R Osuna… - 2023 - Eur Respiratory Soc
Diagnosis of interstitial lung diseases (ILD) is difficult to perform. Extracellular vesicles (EVs)
facilitate cell-to-cell communication. Our goal aimed to investigate EVs markers in …