PURPOSE Germline testing (GT) is a central feature of prostate cancer (PCA) treatment,
management, and hereditary cancer assessment. Critical needs include optimized …

Purpose Guidelines are limited for genetic testing for prostate cancer (PCA). The goal of this
conference was to develop an expert consensus-driven working framework for …

Background Genetic testing capability and guidelines are rapidly expanding to assess
inherited prostate cancer (PCA). Clinical genetic data from multigene testing can provide …

Background Germline genetic testing increasingly identifies advanced prostate cancer
(PCa) patients who are candidates for precision therapies. The Prostate Cancer Clinical …

Germline genetic testing is now routinely recommended for patients with prostate cancer
(PCa) because of expanded guidelines and options for targeted treatments. However …

Inherited genetic mutations can significantly increase the risk for prostate cancer (PC), may
be associated with aggressive disease and poorer outcomes, and can have hereditary …

Purpose: Until recently the role of germline genetics in prostate cancer care was not well
defined. While important questions remain, we reviewed the current understanding of …

Genetic testing for prostate cancer is rapidly growing and is increasingly being driven by
precision medicine. Rates of germline pathogenic variants have been reported in up to 15 …

Importance Prostate cancer is the third leading cause of cancer-related death in men in the
United States. Although serious, most of these diagnoses are not terminal. Inherited risk for …

Background Genetic testing, to identify pathogenic or likely pathogenic variants in prostate
cancer, is valuable in guiding treatment decisions for men with prostate cancer and to inform …