[HTML][HTML] Emerging role of circular RNAs in hepatocellular carcinoma immunotherapy

T Abaza, MKA El-Aziz, KA Daniel, P Karousi… - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is a highly fatal malignancy with limited therapeutic options
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …

[HTML][HTML] Circular RNAs and hepatocellular carcinoma: new epigenetic players with diagnostic and prognostic roles

K Aishanjiang, X Wei, Y Fu, X Lin, Y Ma, J Le… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
worldwide. Due to the lack of potent diagnosis and prognosis biomarkers and effective …

[HTML][HTML] Circular RNAs in hepatocellular carcinoma: Emerging functions to clinical significances

Y Zhang, Y Wang - Frontiers in oncology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver and carries
high morbidity and mortality. Diagnosing HCC at an early stage is challenging. Therefore …

[HTML][HTML] Circular RNAs: characteristics, function and clinical significance in hepatocellular carcinoma

M Wang, F Yu, P Li - Cancers, 2018 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide. HCC patients are commonly diagnosed at an advanced stage, for which highly …

[HTML][HTML] The roles of circRNAs in liver cancer immunity

Y Tang, M Jiang, HM Jiang, ZJ Ye, YS Huang… - Frontiers in …, 2021 - frontiersin.org
Circular RNAs (circRNAs) are stable covalently closed non-coding RNAs (ncRNAs). Many
studies indicate that circRNAs are involved in the pathological and physiological processes …

Circular RNA circ-102,166 acts as a sponge of miR-182 and miR-184 to suppress hepatocellular carcinoma proliferation and invasion

R Li, Y Deng, J Liang, Z Hu, X Li, H Liu, G Wang, B Fu… - Cellular Oncology, 2021 - Springer
Abstract Purpose Multiple circular RNAs (circRNAs) have been reported to be dysregulated
in hepatocellular carcinoma (HCC). However, their functions and modes of action are still …

[HTML][HTML] Current molecular biology and therapeutic strategy status and prospects for circRNAs in HBV-associated hepatocellular carcinoma

R Liao, L Liu, J Zhou, X Wei, P Huang - Frontiers in Oncology, 2021 - frontiersin.org
Circular RNAs (circRNAs) are newly classified noncoding RNA (ncRNA) members with a
covalently closed continuous loop structure that are involved in immune responses against …

[HTML][HTML] The potential regulatory roles of circular RNAs in tumor immunology and immunotherapy

Z Fang, C Jiang, S Li - Frontiers in immunology, 2021 - frontiersin.org
Circular RNAs (circRNAs) are covalently closed RNA molecules in eukaryotes with features
of high stability, tissue-specific and cell-specific expression. According to their biogenesis …

Role of circular RNAs in disease progression and diagnosis of cancers: An overview of recent advanced insights

SU Khan, MU Khan, MI Khan, AA Fadahunsi… - International journal of …, 2022 - Elsevier
Tumor microenvironment (TME) is a crucial regulator of tumor progression and cells in the
TME release a number of molecules that are responsible for anaplasticity, invasion …

Circular RNAs in hepatocellular carcinoma: biomarkers, functions and mechanisms

L Qiu, H Xu, M Ji, D Shang, Z Lu, Y Wu, Z Tu, H Liu - Life sciences, 2019 - Elsevier
Hepatocellular carcinoma (HCC), a leading cause of cancer-related death with high invasive
and metastatic potential, has a low survival rate. To improve the survival and quality of life in …