Besides its important role in embryonic development and homeostatic self-renewal in adult
tissues, Wnt/β-catenin signaling exerts both anti-inflammatory and proinflammatory …

Cross-regulation between the Wnt and nuclear factor (NF)-κB signaling pathways has
emerged as an important area for the regulation of a diverse array of genes and pathways …

Emerging scientific evidence indicates that inflammation is a critical component of tumor
promotion and progression. Most cancers originate from sites of chronic irritation, infections …

Wnt proteins comprise a large family of highly conserved glycoproteins known for their role
in development, cell fate specification, tissue regeneration, and tissue homeostasis …

Inflammation and oxidative stress are common and co-substantial pathological processes
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …

The Wnt/β-catenin pathway is an evolutionarily conserved signaling pathway critical for
several biological processes. An aberrant Wnt/β-catenin signaling is linked to several …

The human inducible nitric oxide synthase (hiNOS) gene is regulated by nuclear factor κB
(NF-κB) and has recently been shown to be a target of the Wnt/β-catenin pathway. In this …

The Wnt-β-catenin signaling pathway is an evolutionarily conserved cell-cell communication
system that is important for stem cell renewal, cell proliferation and cell differentiation both …

Wnt/β-catenin signalling plays essential roles in embryonic development as well as tissue
homoeostasis in adults. Thus abnormal regulation of Wnt/β-catenin signalling is linked to a …

Wnt5a is the prototypical activator of the non-canonical Wnt pathways, and its
overexpression has been implicated in the progression of several tumor types by promoting …