Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological …

L Elia, R Contu, M Quintavalle, F Varrone, C Chimenti… - Circulation, 2009 - Am Heart Assoc
Background—MicroRNAs (miRNAs/miRs) are small conserved RNA molecules of 22
nucleotides that negatively modulate gene expression primarily through base paring to the …

Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy

M Tatsuguchi, HY Seok, TE Callis, JM Thomson… - Journal of molecular and …, 2007 - Elsevier
MicroRNAs (miRNAs) are a recently discovered class of∼ 22-nucleotide regulatory RNAs
that post-transcriptionally regulate gene expression. We have recently demonstrated that …

MicroRNAs: novel regulators in cardiac development and disease

T Thum, D Catalucci, J Bauersachs - Cardiovascular research, 2008 - academic.oup.com
MicroRNAs (miRNAs) are endogenous, small ribonucleotides regulating the translation of
target messenger RNAs that have been shown to be involved in orchestrating growth …

Muscling through the microRNA world

TE Callis, Z Deng, JF Chen… - … biology and medicine, 2008 - journals.sagepub.com
microRNAs (miRNAs) are a class of highly conserved small non-coding RNAs that
negatively regulate gene expression post-transcriptionally. The emerging field of miRNA …

MicroRNAs in cardiomyocyte development

AP Malizia, DZ Wang - Wiley Interdisciplinary Reviews …, 2011 - Wiley Online Library
MicroRNAs (miRNAs) negatively regulate gene expression at the post‐transcriptional level,
primarily by base‐pairing with the 3′‐untranslated region (3′‐UTR) of their target mRNAs …

miRNA in cardiac development and regeneration

Z Ouyang, K Wei - Cell Regeneration, 2021 - Springer
Ischemic heart disease is one of the main causes of morbidity and mortality in the world. In
adult mammalian hearts, most cardiomyocytes are terminally differentiated and have …

microRNAs and muscle disorders

JF Chen, TE Callis, DZ Wang - Journal of cell science, 2009 - journals.biologists.com
MicroRNAs (miRNAs) are a class of non-coding regulatory RNAs of∼ 22 nucleotides in
length. miRNAs are highly conserved across a number of species, including plants, worms …

MicroRNAs in skeletal and cardiac muscle development

TE Callis, JF Chen, DZ Wang - DNA and cell biology, 2007 - liebertpub.com
MicroRNAs (miRNAs) are a recently discovered class of small non-coding RNAs, which
are∼ 22 nucleotides in length. miRNAs negatively regulate gene expression by …

MicroRNAs play an essential role in the development of cardiac hypertrophy

D Sayed, C Hong, IY Chen, J Lypowy… - Circulation …, 2007 - Am Heart Assoc
MicroRNAs are naturally existing, small, noncoding RNA molecules that downregulate
posttranscriptional gene expression. Their expression pattern and function in the heart …

microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart

A Heidersbach, C Saxby, K Carver-Moore, Y Huang… - Elife, 2013 - elifesciences.org
microRNA-1 (miR-1) is an evolutionarily conserved, striated muscle-enriched miRNA. Most
mammalian genomes contain two copies of miR-1, and in mice, deletion of a single locus …