[HTML][HTML] New drugs are not enough‑drug repositioning in oncology: An update

RG Armando… - … Journal of Oncology, 2020 - spandidos-publications.com
Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that
are already known for use treating other diseases. The advantages of this are that several …

[HTML][HTML] The prince and the pauper. A tale of anticancer targeted agents

A Dueñas-González, P García-López, LA Herrera… - Molecular cancer, 2008 - Springer
Cancer rates are set to increase at an alarming rate, from 10 million new cases globally in
2000 to 15 million in 2020. Regarding the pharmacological treatment of cancer, we currently …

Drug repositioning in cancer: The current situation in Japan

T Masuda, Y Tsuruda, Y Matsumoto, H Uchida… - Cancer …, 2020 - Wiley Online Library
Cancer is a leading cause of death worldwide, and the incidence continues to increase.
Despite major research aimed at discovering and developing novel and effective anticancer …

Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds

R Wuerth, S Thellung, A Bajetto, M Mazzanti, T Florio… - Drug discovery today, 2016 - Elsevier
Highlights•De novo anticancer drug discovery is challenging and repurposing in oncology is
a promising field.•Drug repositioning increasingly emerges as faster, cheaper and …

[HTML][HTML] Recent advances in drug repositioning for the discovery of new anticancer drugs

JS Shim, JO Liu - International journal of biological sciences, 2014 - ncbi.nlm.nih.gov
Drug repositioning (also referred to as drug repurposing), the process of finding new uses of
existing drugs, has been gaining popularity in recent years. The availability of several …

Repositioning drugs and biologics: Retargeting old/existing drugs for potential new therapeutic applications.

BS Sekhon - Journal of Pharmaceutical Education & …, 2013 - search.ebscohost.com
Drug discovery and development is a time consuming, costly and risky venture. As an
alternative approach, pharmaceutical companies have adopted drug repositioning (also …

The value of drug repositioning in the current pharmaceutical market.

EL Tobinick - Drug news & perspectives, 2009 - europepmc.org
Drug repositioning is the process of developing new indications for existing drugs or
biologics. Increasing interest in drug repositioning has occurred due to sustained high …

Systems biology based drug repositioning for development of cancer therapy

B Turanli, O Altay, J Borén, H Turkez, J Nielsen… - Seminars in cancer …, 2021 - Elsevier
Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …

Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work

R Kumar, S Harilal, SV Gupta, J Jose, MS Uddin… - European journal of …, 2019 - Elsevier
Drug discovery and development are long and financially taxing processes. On an average
it takes 12–15 years and costs 1.2 billion USD for successful drug discovery and approval …

Drug combination therapy increases successful drug repositioning

W Sun, PE Sanderson, W Zheng - Drug discovery today, 2016 - Elsevier
Highlights•Publications for drug repositioning have drastically increased in past five
years.•Different types of drug repositioning and available resources have been …