BioSamplr: An open source, low cost automated sampling system for bioreactors

JP Efromson, S Li, MD Lynch - HardwareX, 2021 - Elsevier
Autosampling from bioreactors reduces error, increases reproducibility and offers improved
aseptic handling when compared to manual sampling. Additionally, autosampling greatly …

Implementing an automated reactor sampling system for monitoring cell culture bioreactors

L Speciner, G Barringer, J Perez… - 234th ACS National …, 2007 - aiche.confex.com
Monitoring of cell culture bioreactors is critical to process control and optimization. Currently,
offline sampling is used in various cell culture operations. This process is time consuming …

[PDF][PDF] An automatic aseptic bioreactor sampling system

GKE Seifert, PP Matteau - Biotechnology and bioengineering, 1988 - Wiley Online Library
Few sampling systems supplied with laboratory fermenters are easily modified for
unattended aseptic sampling. Most commercial sampling systems are manually operated …

An automated, pressure-driven sampling device for harvesting from liquid cultures for genomic and biochemical analyses

AD Aragon, GA Quinones, C Allen, J Thomas… - Journal of …, 2006 - Elsevier
Here we describe an automated, pressure-driven, sampling device for harvesting 10 to 30
ml samples, in replicate, with intervals as short as 10 s. Correlation between biological …

Samasy: an automated system for sample selection and robotic transfer

CL Cario, JS Witte - Biotechniques, 2018 - Taylor & Francis
Sample automation and management is increasingly important as the number and size of
population-scale and high-throughput projects grow. This is particularly the case in large …

Cell culture monitoring via an auto‐sampler and an integrated multi‐functional off‐line analyzer

GE Derfus, D Abramzon, M Tung, D Chang… - Biotechnology …, 2010 - Wiley Online Library
Mammalian cell‐based bioprocesses are used extensively for production of therapeutic
proteins. Off‐line monitoring of such cultivations via manual sampling is often labor …

Setting up an automated biomanufacturing laboratory

M Pavan - Synthetic Gene Circuits: Methods and Protocols, 2021 - Springer
Laboratory automation is a key enabling technology for genetic engineering that can lead to
higher throughput, more efficient and accurate experiments, better data management and …

Aquarium: open-source laboratory software for design, execution and data management

J Vrana, O de Lange, Y Yang, G Newman… - Synthetic …, 2021 - academic.oup.com
Automation has been shown to improve the replicability and scalability of biomedical and
bioindustrial research. Although the work performed in many labs is repetitive and can be …

'TeeBot': a high throughput robotic fermentation and sampling system

N van Holst Pellekaan, ME Walker, TL Watson… - Fermentation, 2021 - mdpi.com
When fermentation research requires the comparison of many strains or conditions, the
major bottleneck is a technical one. Microplate approaches are not able to produce …

An intelligent automation platform for rapid bioprocess design

T Wu, Y Zhou - Journal of laboratory automation, 2014 - journals.sagepub.com
Bioprocess development is very labor intensive, requiring many experiments to characterize
each unit operation in the process sequence to achieve product safety and process …