Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral …
WG Glass, MJ Hickey, JL Hardison, MT Liu… - The Journal of …, 2004 - journals.aai.org
Intracerebral infection of mice with mouse hepatitis virus, a member of the Coronaviridae
family, reproducibly results in an acute encephalomyelitis that progresses to a chronic …
family, reproducibly results in an acute encephalomyelitis that progresses to a chronic …
Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple …
MT Liu, HS Keirstead, TE Lane - The Journal of Immunology, 2001 - journals.aai.org
Intracerebral infection of mice with mouse hepatitis virus (MHV) results in an acute
encephalomyelitis followed by a chronic demyelinating disease with clinical and histological …
encephalomyelitis followed by a chronic demyelinating disease with clinical and histological …
CCL2 transgene expression in the central nervous system directs diffuse infiltration of CD45highCD11b+ monocytes and enhanced Theiler's murine …
JL Bennett, A Elhofy, MC Dal Canto, M Tani… - Journal of …, 2003 - Springer
CCL2 is a member of the CC chemokine family that mediates the migration and recruitment
of monocytes and T cells and has been identified in the central nervous system (CNS) …
of monocytes and T cells and has been identified in the central nervous system (CNS) …
Functional Expression of Chemokine Receptor CCR5 on CD4+ T Cells during Virus-Induced Central Nervous System Disease
WG Glass, TE Lane - Journal of virology, 2003 - Am Soc Microbiol
Intracranial infection of C57BL/6 mice with mouse hepatitis virus (MHV) results in an acute
encephalomyelitis followed by a demyelinating disease similar in pathology to the human …
encephalomyelitis followed by a demyelinating disease similar in pathology to the human …
Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease
S Eltayeb, D Sunnemark, AL Berg, G Nordvall… - Journal of …, 2003 - Elsevier
We have studied the role of the chemokine receptor CCR1 during the effector stage of
myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis …
myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis …
CCR1 deficiency increases susceptibility to fatal coronavirus infection of the central nervous system
MJ Hickey, KS Held, E Baum, JL Gao, PM Murphy… - Viral …, 2007 - liebertpub.com
The role of CC chemokine receptor 1 (CCR1) in host defense and disease development was
determined in a model of viral-induced neurologic disease. Intracerebral (IC) infection of …
determined in a model of viral-induced neurologic disease. Intracerebral (IC) infection of …
CC chemokine receptor 8 in the central nervous system is associated with phagocytic macrophages
C Trebst, SM Staugaitis, P Kivisäkk, D Mahad… - The American journal of …, 2003 - Elsevier
CC chemokine receptor 8 (CCR8) has been detected in vitro on type 2 helper and regulatory
lymphocytes, which might exert beneficial functions in multiple sclerosis (MS) and on …
lymphocytes, which might exert beneficial functions in multiple sclerosis (MS) and on …
Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis
Chemokines are a superfamily of chemotactic cytokines that play an important role in
leukocyte trafficking and have been implicated as functional mediators of immunopathology …
leukocyte trafficking and have been implicated as functional mediators of immunopathology …
CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis
BT Fife, GB Huffnagle, WA Kuziel… - The Journal of …, 2000 - rupress.org
Experimental autoimmune encephalomyelitis (EAE) is a CD4+ T lymphocyte–mediated
disease of the central nervous system (CNS) characterized by mononuclear cell infiltration …
disease of the central nervous system (CNS) characterized by mononuclear cell infiltration …
Reduced macrophage infiltration and demyelination in mice lacking the chemokine receptor CCR5 following infection with a neurotropic coronavirus
WG Glass, MT Liu, WA Kuziel, TE Lane - Virology, 2001 - Elsevier
Studies were performed to investigate the contributions of the CC chemokine receptor CCR5
in host defense and disease development following intracranial infection with mouse …
in host defense and disease development following intracranial infection with mouse …
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