[HTML][HTML] Metabolic perturbations in pregnant rats exposed to low-dose perfluorooctanesulfonic acid: an integrated multi-omics analysis

G Yu, J Wang, Y Liu, T Luo, X Meng, R Zhang… - Environment …, 2023 - Elsevier
Emerging epidemiological evidence has linked per-and polyfluoroalkyl substances (PFAS)
exposure could be linked to the disturbance of gestational glucolipid metabolism, but the …

Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat …

X Meng, G Yu, T Luo, R Zhang, J Zhang, Y Liu - Chemosphere, 2023 - Elsevier
Emerging epidemiological evidence indicates potential associations between gestational
perfluorobutane sulfonate (PFBS) exposure and adverse metabolic outcomes in offspring …

[HTML][HTML] Transcriptomic and metabolomic profile changes in the liver of Sprague Dawley rat offspring after maternal PFOS exposure during gestation and lactation

R Zhang, G Yu, T Luo, X Zeng, Y Sun, B Huang… - Ecotoxicology and …, 2024 - Elsevier
Epidemiological and experimental research has indicated an association between
perfluorooctane sulfonate (PFOS) exposure and liver disease. However, the potential …

In utero perfluorooctane sulfonate exposure causes low body weights of fetal rats: A mechanism study

X Li, L Ye, Y Ge, K Yuan, Y Zhang, Y Liang, J Wei… - Placenta, 2016 - Elsevier
Objectives The objective of the present study is to investigate the mechanism of
perfluorooctane sulfonate-induced low body weight of fetus by analysis of glucocorticoid …

Effects of In Utero PFOS Exposure on Epigenetics and Metabolism in Mouse Fetal Livers

TC Ho, HT Wan, WK Lee, TKY Lam, X Lin… - Environmental …, 2023 - ACS Publications
Prenatal exposure to perfluorooctanesulfonate (PFOS) increases fetus' metabolic risk;
however, the investigation of the underlying mechanism is limited. In this study, pregnant …

[HTML][HTML] Exposure to legacy and novel perfluoroalkyl substance disturbs the metabolic homeostasis in pregnant women and fetuses: A metabolome-wide association …

Y Li, X Lu, N Yu, A Li, T Zhuang, L Du, S Tang… - Environment …, 2021 - Elsevier
Abstract Background Perfluoroalkyl substances (PFASs) exist extensively and several of
these have been verified to be toxic. Prenatal exposure to PFASs has attracted much …

Early-life perfluorooctanoic acid exposure induces obesity in male offspring and the intervention role of chlorogenic acid

W Shao, J Xu, C Xu, Z Weng, Q Liu, X Zhang… - Environmental …, 2021 - Elsevier
Perfluorooctanoic acid (PFOA) is an emerging organic pollutant (EOP) hazardous to human
health. Effects of maternal PFOA exposure on offspring as well as the underlying …

[HTML][HTML] Environmental exposure to perfluoroalkyl substances in early pregnancy, maternal glucose homeostasis and the risk of gestational diabetes: A prospective …

G Yu, M Jin, Y Huang, R Aimuzi, T Zheng, M Nian… - Environment …, 2021 - Elsevier
Background Humans are widely exposed to environmental perfluoroalkyl substances
(PFAS), which may affect glucose homeostasis. However, research linking PFAS exposure …

[HTML][HTML] Assessing the human health risks of perfluorooctane sulfonate by in vivo and in vitro studies

Z Zeng, B Song, R Xiao, G Zeng, J Gong, M Chen… - Environment …, 2019 - Elsevier
The wide use of perfluorooctane sulfonate (PFOS) has led to increasing concern about its
human health risks over the past decade. In vivo and in vitro studies are important and …

Exposure to per-and polyfluoroalkyl substances as a risk factor for gestational diabetes mellitus through interference with glucose homeostasis

C Xu, L Zhang, Q Zhou, J Ding, S Yin, X Shang… - Science of The Total …, 2022 - Elsevier
Per-and polyfluoroalkyl substances (PFASs) are hypothesized to trigger gestational diabetes
mellitus (GDM) through modulation of glucose metabolism. However, studies investigating …