Improvement of base editors and prime editors advances precision genome engineering in plants

K Hua, P Han, JK Zhu - Plant physiology, 2022 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated
protein (Cas)-mediated gene disruption has revolutionized biomedical research as well as …

The CRISPR/Cas9 revolution continues: from base editing to prime editing in plant science

Y Li, W Li, J Li - Journal of Genetics and Genomics, 2021 - Elsevier
The ability to precisely inactivate or modify genes in model organisms helps us understand
the mysteries of life. Clustered regularly interspaced short palindromic repeats …

[HTML][HTML] Base editing: The ever expanding clustered regularly interspaced short palindromic repeats (CRISPR) tool kit for precise genome editing in plants

MB Monsur, G Shao, Y Lv, S Ahmad, X Wei, P Hu… - Genes, 2020 - mdpi.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated
protein 9 (Cas9), a newly developed genome-editing tool, has revolutionized animal and …

Precise plant genome editing using base editors and prime editors

KA Molla, S Sretenovic, KC Bansal, Y Qi - Nature Plants, 2021 - nature.com
The development of CRISPR–Cas systems has sparked a genome editing revolution in
plant genetics and breeding. These sequence-specific RNA-guided nucleases can induce …

Breakthrough in CRISPR/Cas system: Current and future directions and challenges

A Ali, MM Zafar, Z Farooq, SR Ahmed… - Biotechnology …, 2023 - Wiley Online Library
Targeted genome editing (GE) technology has brought a significant revolution in fictional
genomic research and given hope to plant scientists to develop desirable varieties. This …

[HTML][HTML] CRISPR base editing and prime editing: DSB and template-free editing systems for bacteria and plants

Z Jiang, X Hong, S Zhang, R Yao, YI Xiao - Synthetic and Systems …, 2020 - Elsevier
Abstract CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats-
CRISPR associated) has been extensively exploited as a genetic tool for genome editing …

[HTML][HTML] Applications and prospects of CRISPR/Cas9-mediated base editing in plant breeding

Y Li, J Liang, B Deng, Y Jiang, J Zhu, L Chen… - Current Issues in …, 2023 - mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein
9 system (Cas9) has been used at length to optimize multiple aspects of germplasm …

Genome editing for plant research and crop improvement

X Zhan, Y Lu, JK Zhu, JR Botella - Journal of Integrative Plant …, 2021 - Wiley Online Library
The advent of clustered regularly interspaced short palindromic repeat (CRISPR) has had a
profound impact on plant biology, and crop improvement. In this review, we summarize the …

Targeted genome-modification tools and their advanced applications in crop breeding

B Li, C Sun, J Li, C Gao - Nature Reviews Genetics, 2024 - nature.com
Crop improvement by genome editing involves the targeted alteration of genes to improve
plant traits, such as stress tolerance, disease resistance or nutritional content. Techniques …

Updates on gene editing and its applications

H Puchta, J Jiang, K Wang, Y Zhao - Plant Physiology, 2022 - academic.oup.com
Recent advancements in gene editing provide unprecedented tools for plant biology
research and offer unlimited potential for improving existing crops and de novo …