Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …
[PDF][PDF] Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients
Recent reports suggest an association between COVID-19 and altered olfactory function.
Here we analyze bulk and single cell RNA-Seq datasets to identify cell types in the olfactory …
Here we analyze bulk and single cell RNA-Seq datasets to identify cell types in the olfactory …
SARS-CoV-2 receptors and entry genes are expressed in the human olfactory neuroepithelium and brain
L Fodoulian, J Tuberosa, D Rossier, M Boillat, C Kan… - Iscience, 2020 - cell.com
Reports indicate an association between COVID-19 and anosmia, as well as the presence
of SARS-CoV-2 virions in the olfactory bulb. To test whether the olfactory neuroepithelium …
of SARS-CoV-2 virions in the olfactory bulb. To test whether the olfactory neuroepithelium …
Mechanisms of SARS-CoV-2-associated anosmia
Anosmia, the loss of the sense of smell, is one of the main neurological manifestations of
COVID-19. Although the SARS-CoV-2 virus targets the nasal olfactory epithelium, current …
COVID-19. Although the SARS-CoV-2 virus targets the nasal olfactory epithelium, current …
SARS-CoV-2 infection in the mouse olfactory system
Q Ye, J Zhou, Q He, RT Li, G Yang, Y Zhang, SJ Wu… - Cell discovery, 2021 - nature.com
SARS-CoV-2 infection causes a wide spectrum of clinical manifestations in humans, and
olfactory dysfunction is one of the most predictive and common symptoms in COVID-19 …
olfactory dysfunction is one of the most predictive and common symptoms in COVID-19 …
Anosmia in COVID-19: underlying mechanisms and assessment of an olfactory route to brain infection
R Butowt, CS von Bartheld - The Neuroscientist, 2021 - journals.sagepub.com
In recent months it has emerged that the novel coronavirus—responsible for the COVID-19
pandemic—causes reduction of smell and taste in a large fraction of patients. The …
pandemic—causes reduction of smell and taste in a large fraction of patients. The …
Expression of the SARS-CoV-2 entry proteins, ACE2 and TMPRSS2, in cells of the olfactory epithelium: identification of cell types and trends with age
K Bilinska, P Jakubowska… - ACS chemical …, 2020 - ACS Publications
The COVID-19 pandemic revealed that there is a loss of smell in many patients, including in
infected but otherwise asymptomatic individuals. The underlying mechanisms for the …
infected but otherwise asymptomatic individuals. The underlying mechanisms for the …
COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters
GD De Melo, F Lazarini, S Levallois… - Science translational …, 2021 - science.org
Whereas recent investigations have revealed viral, inflammatory, and vascular factors
involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung …
involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung …
[HTML][HTML] SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways
Loss of olfactory function has been commonly reported in SARS-CoV-2 infections. Recovery
from anosmia is not well understood. Previous studies showed that sustentacular cells, and …
from anosmia is not well understood. Previous studies showed that sustentacular cells, and …
Pathogenesis of olfactory disorders in COVID-19
L Ziuzia-Januszewska, M Januszewski - Brain sciences, 2022 - mdpi.com
Since the outbreak of the SARS-CoV-2 pandemic, olfactory disorders have been reported as
a frequent symptom of COVID-19; however, its pathogenesis is still debated. The aim of this …
a frequent symptom of COVID-19; however, its pathogenesis is still debated. The aim of this …
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