The aim of the present study is to determine the potential toxicity of the therapeutic doses of
rosuvastatin in Wistar albino rats. A total of 80 adult Wistar male albino rats were divided …

The study was designed to investigate the biochemical and histological changes in mice that
consuming diet rich with animal and vegetable fats that caused obesity, which treated with …

Background: Simvastatin is an effective hypocholesterolemic drug that inhibits cholesterol
synthesis selectively in the liver but at the same time could have potential side effects on the …

In this study, we evaluated the ultrastructural findings of kidney with systemic administration
of different doses of atorvastatin in a rat model. Statins may have anti-inflammatory effects …

Objective: This experimental study aimed to evaluate the statin-induced hepatotoxicity in
albino rats, as well as to compare the potential hepatotoxicity between atorvastatin and …

Lifestyle changes, such as poor eating habits and a reduction in physical exercise, have
impaired human lipid profiles. Statins are widely used to treat dyslipidemias, of which …

Results: Compare with the control group, in atorvastatin groups for two periods can effect by
significant increase (p< 0.05) in activities of liver enzymes alkaline phosphatase (ALP) …

The prevalence of obesity has been rising alarmingly and it has now become a global
concern causing an enormous economic burden on the health care system. Obesity is …

Background: Rosuvastatin can decrease low-density lipoprotein cholesterol to the optimal
goals. Adverse effects of rosuvastatin involve kidneys. Multiple studies explained that these …

Background: Atorvastatin is a first-line lipid-lowering therapy in patients at low to high risk of
coronary heart disease. In animals, statin intake reduces sperm parameters. Atorvastatin …