Chitosan based polymer/bioglass composites for tissue engineering applications

D Vukajlovic, J Parker, O Bretcanu… - Materials Science and …, 2019 - Elsevier
Composite scaffolds formed from polymers and bioglasses have been widely explored for
applications in regenerative medicine as they have suitable organic/inorganic structures and …

Genipin-crosslinked chitosan/gelatin blends for biomedical applications

V Chiono, E Pulieri, G Vozzi, G Ciardelli… - Journal of Materials …, 2008 - Springer
Blends between chitosan (CS) and gelatin (G) with various compositions (CS/G 0/100 20/80,
40/60, 60/40 100/0 w/w) were produced, as candidate materials for biomedical applications …

How can genipin assist gelatin/carbohydrate chitosan scaffolds to act as replacements of load-bearing soft tissues?

M Sarem, F Moztarzadeh, M Mozafari - Carbohydrate polymers, 2013 - Elsevier
In the engineering of soft tissues, designing the scaffolds with adequate strength and
controllable biodegradation properties are essential. To fulfill such design criteria …

Genipin‐cross‐linked collagen/chitosan biomimetic scaffolds for articular cartilage tissue engineering applications

LP Yan, YJ Wang, L Ren, G Wu… - … Research Part A, 2010 - Wiley Online Library
In this study, genipin‐cross‐linked collagen/chitosan biodegradable porous scaffolds were
prepared for articular cartilage regeneration. The influence of chitosan amount and genipin …

Effects of different cross-linking conditions on the properties of genipin-cross-linked chitosan/collagen scaffolds for cartilage tissue engineering

L Bi, Z Cao, Y Hu, Y Song, L Yu, B Yang, J Mu… - Journal of Materials …, 2011 - Springer
A cross-linking reagent is required to improve mechanical strength and degradation
properties of biopolymers for tissue engineering. To find the optimal preparative method, we …

Effects of genipin concentration on cross‐linked chitosan scaffolds for bone tissue engineering: structural characterization and evidence of biocompatibility features

S Dimida, A Barca, N Cancelli… - … Journal of Polymer …, 2017 - Wiley Online Library
Genipin (GN) is a natural molecule extracted from the fruit of Gardenia jasminoides Ellis
according to modern microbiological processes. Genipin is considered as a favorable cross …

Genipin-crosslinked chitosan gels and scaffolds for tissue engineering and regeneration of cartilage and bone

RAA Muzzarelli, M El Mehtedi, C Bottegoni, A Aquili… - Marine drugs, 2015 - mdpi.com
The present review article intends to direct attention to the technological advances made
since 2009 in the area of genipin-crosslinked chitosan (GEN-chitosan) hydrogels. After a …

Hydrogel–based biopolymers for regenerative medicine applications: a critical review

SO Ebhodaghe - International Journal of Polymeric Materials and …, 2022 - Taylor & Francis
There is need to advance the field of regenerative medicine through a comprehensive
analysis of common biomaterials application. Since lots of studies on tissue engineering …

Physical properties imparted by genipin to chitosan for tissue regeneration with human stem cells: A review

RAA Muzzarelli, M El Mehtedi, C Bottegoni… - International journal of …, 2016 - Elsevier
Genipin is a fully assessed non-cytotoxic crosslinking compound. The chitosan| genipin
physical properties such as morphology, roughness, porosity, hydrophilicity, ζ-potential …

Crosslinked fibrin gels for tissue engineering: two approaches to improve their properties

TC Gamboa‐Martínez, V Luque‐Guillén… - … Research Part A, 2015 - Wiley Online Library
Fibrin is a protein that can be used as an ideal scaffolding material to promote tissue
regeneration. In order to enhance its physical properties in this study a natural crosslinker …