Background and objectives: Cyclophosphamide (CPA) is an alkylating agent that is used for
the management of various types of malignancies and as an immunosuppressive agent for …

Many natural flavonoids can activate nuclear factor erythroid 2-related factor 2 (Nrf2), which
is pivotal for alleviating various diseases related to inflammation and oxidative stress …

Cyclophosphamide (CP) is an antineoplastic drug commonly used worldwide. Despite its
spread, it causes fatal organ toxicity. Lung toxicity is a serious side effect of CP. Actually, in …

Lipopolysaccharides (LPS), the lipid component of gram-negative bacterial cell wall, is
recognized as the key factor in acute lung inflammation and is found to exhibit severe …

Sepsis is a serious medical problem and is one of the main causes of high mortality in
intensive care units. Fifty percent of patients with severe sepsis will develop acute lung injury …

Cyclophosphamide (CP)-induced lung toxicity is a remaining obstacle against the beneficial
use of this chemotherapeutic agent. More considerations were given to the role of Alogliptin …

The present study aims to investigate the impacts and mechanisms of silymarin on paraquat
(PQ)‐induced lung injury in vivo and in vitro. In in vivo experiments, a total of 32 male …

Background Bleomycin (BLM) is a chemotherapy drug used to treat cancer, one of which
side effects is that it can lead to pulmonary fibrosis (PF). Atractylenoide III (AtrIII), derived …

Background Doxorubicin (DOX) is a potent anticancer chemotherapeutic agent whose
clinical application is substantially constrained by its cardiotoxicity. The pathophysiology of …

Background: Eupatilin is an active flavon extracted from the Artemisia species and has
properties such as antioxidant, anti-inflammatory, and anti-cancer. We examined the effect of …