The mechanism of kaempferol induced apoptosis and inhibited proliferation in human cervical cancer SiHa cell: From macro to nano

LY Tu, HH Bai, JY Cai, SP Deng - Scanning, 2016 - Wiley Online Library
Kaempferol has been identified as a potential cancer therapeutic agent by an increasing
amount of evidences. However, the changes in the topography of cell membrane induced by …

Kaempferol regresses carcinogenesis through a molecular cross talk involved in proliferation, apoptosis and inflammation on human cervical cancer cells, HeLa

N Afroze, S Pramodh, AG Almutary, TA Rizvi, N Rais… - Applied Sciences, 2022 - mdpi.com
Kaempferol, a flavonoid, contains a plethora of therapeutic properties and has demonstrated
its efficacy against cancer. This study aims to unravel the molecular targets that are being …

Kaempferol increases apoptosis in human cervical cancer HeLa cells via PI3K/AKT and telomerase pathways

E Kashafi, M Moradzadeh, A Mohamadkhani… - Biomedicine & …, 2017 - Elsevier
Cervical cancer is one of the most frequent cancers in women worldwide. Defects in the
apoptotic pathways are responsible for both the disease pathogenesis and its therapy …

[HTML][HTML] Kaempferol suppresses proliferation and induces cell cycle arrest, apoptosis, and DNA damage in breast cancer cells

L Zhu, L Xue - Oncology research, 2019 - ncbi.nlm.nih.gov
Kaempferol is a flavonoid that has been extensively investigated owing to its antitumor
effects. Nevertheless, little is known about its underlying mechanisms of action. We aimed to …

[PDF][PDF] Kaempferol exerts anti-proliferative effects on human ovarian cancer cells by inducing apoptosis, G0/G1 cell cycle arrest and modulation of MEK/ERK and …

S Yang, L Si, Y Jia, W Jian, Q Yu, M Wang, R Lin - J buon, 2019 - jbuon.com
Purpose: Ovarian cancer causes significant mortality in women and is one of the most
prevalent types of gynaecological cancer world over. Ovarian cancer is often diagnosed at …

Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria‐dependent pathway in human osteosarcoma U‐2 OS cells

WW Huang, YJ Chiu, MJ Fan, HF Lu… - Molecular nutrition & …, 2010 - Wiley Online Library
Kaempferol is a natural flavonoid. Previous studies have reported that kaempferol has anti‐
proliferation activities and induces apoptosis in many cancer cell lines. However, there are …

Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells

HS Lee, HJ Cho, R Yu, KW Lee, HS Chun… - International journal of …, 2014 - mdpi.com
We previously noted that kaempferol, a flavonol present in vegetables and fruits, reduced
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …

Anti-cancer effect and underlying mechanism (s) of kaempferol, a phytoestrogen, on the regulation of apoptosis in diverse cancer cell models

SH Kim, KC Choi - Toxicological research, 2013 - Springer
Phytoestrogens exist in edible compounds commonly found in fruits or plants. For long
times, phytoestrogens have been used for therapeutic treatments against human diseases …

Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc

H Luo, MK Daddysman, GO Rankin, BH Jiang… - Cancer cell …, 2010 - Springer
Background Ovarian cancer is one of the most significant malignancies in the western world.
Studies showed that Ovarian cancers tend to grow resistance to cisplatin treatment …

Kaempferol induces G2/M cell cycle arrest via checkpoint kinase 2 and promotes apoptosis via death receptors in human ovarian carcinoma A2780/CP70 cells

Y Gao, J Yin, GO Rankin, YC Chen - Molecules, 2018 - mdpi.com
Kaempferol is a widely distributed dietary flavonoid. Epidemiological studies have
demonstrated kaempferol consumption lowers the risk of ovarian cancer. Our previous …