Beyond the visible—imaging the human brain with light

H Obrig, A Villringer - Journal of Cerebral Blood Flow & …, 2003 - journals.sagepub.com
Optical approaches to investigate cerebral function and metabolism have long been applied
in invasive studies. From the neuron cultured in vitro to the exposed cortex in the human …

Non-invasive optical spectroscopy and imaging of human brain function

A Villringer, B Chance - Trends in neurosciences, 1997 - cell.com
Brain activity is associated with changes in optical properties of brain tissue. Optical
measurements during brain activation can assess haemoglobin oxygenation, cytochrome-c …

Functional near‐infrared optical imaging: Utility and limitations in human brain mapping

Y Hoshi - psychophysiology, 2003 - Wiley Online Library
Although near‐infrared spectroscopy (NIRS) was developed as a tool for clinical monitoring
of tissue oxygenation, it also has potential for neuroimaging. A wide range of different NIRS …

A mini-review on functional near-infrared spectroscopy (fNIRS): where do we stand, and where should we go?

V Quaresima, M Ferrari - Photonics, 2019 - mdpi.com
This mini-review is aimed at briefly summarizing the present status of functional near-
infrared spectroscopy (fNIRS) and predicting where the technique should go in the next …

Near-infrared spectroscopy: does it function in functional activation studies of the adult brain?

H Obrig, R Wenzel, M Kohl, S Horst, P Wobst… - International Journal of …, 2000 - Elsevier
Changes in optical properties of biological tissue can be examined by near-infrared
spectroscopy (NIRS). The relative transparency of tissues including the skull to near-infrared …

The fast optical signal—robust or elusive when non-invasively measured in the human adult?

J Steinbrink, FCD Kempf, A Villringer, H Obrig - Neuroimage, 2005 - Elsevier
Near infrared spectroscopy (NIRS) can detect vascular changes in cerebral cortical tissue
elicited by functional stimulation. For some 10 years, another optical signal has been …

Functional near-infrared spectroscopy: current status and future prospects

Y Hoshi - Journal of biomedical optics, 2007 - spiedigitallibrary.org
Near-infrared spectroscopy (NIRS), which was originally designed for clinical monitoring of
tissue oxygenation, has been developing into a useful tool for neuroimaging studies …

Progress of near-infrared spectroscopy and topography for brain and muscle clinical applications

M Wolf, M Ferrari, V Quaresima - Journal of biomedical optics, 2007 - spiedigitallibrary.org
This review celebrates the 30th anniversary of the first in vivo near-infrared (NIR)
spectroscopy (NIRS) publication, which was authored by Professor Frans Jöbsis. At first …

Functional near-infrared spectroscopy (fNIRS): principles and neuroscientific applications

J León-Carrión, U León-Domínguez - Neuroimaging methods, 2012 - books.google.com
1. Introduction fNIRS is a device designed to detect changes in the concentration of
oxygenated (oxyHb) and deoxygenated (deoxyHb) haemoglobin molecules in the blood, a …

Near-infrared oximetry of the brain

PL Madsen, NH Secher - Progress in neurobiology, 1999 - Elsevier
Near-infrared (IR) light easily penetrates biological tissue, and the information offered by in
vivo spectroscopy of cerebral oxygenation is detailed and comes with a high temporal …