New insights have been thrown for understanding the significant role of estrogen on various
systems of humans. Increasing evidences have determined the significant roles of estrogen …

Estrogen mainly binds to estrogen receptors (ERs) to regulate menstrual cycles and
reproduction. The expression of ERalpha (ERα), ERbeta (ERβ), and G-protein-coupled …

Estrogen is a key hormone involved in the development and homeostasis of several tissue
types in both males and females. By binding estrogen receptors, estrogen regulates …

Ovarian hormones play a critical role in facilitating the reproductive process. Although, the
ovaries are known to produce several hormones, the cyclic and time-dependent production …

Estrogens are the key hormones regulating the development and function of reproductive
organs in all vertebrates. Recent evidence indicates that estrogens play important roles in …

Estrogen action plays a crucial role in many processes throughout the human life span,
including development. Estrogens are pivotal in the regulation of female reproduction, but …

Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-
coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian …

Estrogen (E) plays a pivotal role in regulating the female reproductive system, particularly
the ovary. However, the number and type of ovarian genes influenced by estrogen remain to …

Ovarian cancer is still the deadliest of all gynecologic malignancies in women worldwide.
This is attributed to two main features of these tumors, namely,(i) a diagnosis at an advanced …

Seventy-five glorious years have passed since estradiol was discovered by Edward Doisy.
From discovery in the ovaries to delineation of diverse physiological effects, research on …