Genome-wide function of H2B ubiquitylation in promoter and genic regions
K Batta, Z Zhang, K Yen, DB Goffman… - Genes & …, 2011 - genesdev.cshlp.org
Nucleosomal organization in and around genes may contribute substantially to
transcriptional regulation. The contribution of histone modifications to genome-wide …
transcriptional regulation. The contribution of histone modifications to genome-wide …
In Vivo Effects of Histone H3 Depletion on Nucleosome Occupancy and Position in Saccharomyces cerevisiae
AJ Gossett, JD Lieb - PLoS genetics, 2012 - journals.plos.org
Previous studies in Saccharomyces cerevisiae established that depletion of histone H4
results in the genome-wide transcriptional de-repression of hundreds of genes. To probe the …
results in the genome-wide transcriptional de-repression of hundreds of genes. To probe the …
Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants
Ubiquitylation of histone H2B at lysine residue 120 (H2BK120ub) is a prominent histone
posttranslational modification (PTM) associated with the actively transcribed genome …
posttranslational modification (PTM) associated with the actively transcribed genome …
H2B ubiquitylation in transcriptional control: a FACT-finding mission
A little more than 10 years ago, the laboratory of David Allis published two pioneering
papers in Cell (Brownell et al. 1996; Mizzen et al. 1996) demonstrating that the …
papers in Cell (Brownell et al. 1996; Mizzen et al. 1996) demonstrating that the …
H2B ubiquitylation plays a role in nucleosome dynamics during transcription elongation
The monoubiquitylation of histone H2B has been associated with transcription initiation and
elongation, but its role in these processes is poorly understood. We report that H2B …
elongation, but its role in these processes is poorly understood. We report that H2B …
Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation
H Qiu, RV Chereji, C Hu, HA Cole, Y Rawal… - Genome …, 2016 - genome.cshlp.org
Chaperones, nucleosome remodeling complexes, and histone acetyltransferases have
been implicated in nucleosome disassembly at promoters of particular yeast genes, but …
been implicated in nucleosome disassembly at promoters of particular yeast genes, but …
Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate
Various histone modifications decorate nucleosomes within transcribed genes. Among
these, monoubiquitylation of histone H2B (H2Bub1) and methylation of histone H3 on …
these, monoubiquitylation of histone H2B (H2Bub1) and methylation of histone H3 on …
[HTML][HTML] Combinatorial effects of four histone modifications in transcription and differentiation
Nucleosomes are involved in DNA compaction and transcriptional regulation. Yet it is
unclear whether histone modification marks are primary or secondary to transcription and …
unclear whether histone modification marks are primary or secondary to transcription and …
Heavy transcription of yeast genes correlates with differential loss of histone H2B relative to H4 and queued RNA polymerases
HA Cole, J Ocampo, JR Iben, RV Chereji… - Nucleic acids …, 2014 - academic.oup.com
Eukaryotic chromatin is composed of nucleosomes, which contain nearly two coils of DNA
wrapped around a central histone octamer. The octamer contains an H3-H4 tetramer and …
wrapped around a central histone octamer. The octamer contains an H3-H4 tetramer and …
Two strategies for gene regulation by promoter nucleosomes
Chromatin structure is central for the regulation of gene expression, but its genome-wide
organization is only beginning to be understood. Here, we examine the connection between …
organization is only beginning to be understood. Here, we examine the connection between …