Objective. To investigate whether advanced glycation end products (AGEs) induce the
expression of IL-6 and IL-8 through the receptor for AGEs (RAGE)-activated pathways in …

Objective. Advanced glycation end products (AGE) accumulate in articular cartilage with
age. We investigated the effects of AGE in primary-cultured human OA chondrocytes …

Aging and diabetes are known to be the major cause to affect the progression of
osteoarthritis (OA). Advanced glycation end products (AGEs) have been observed to …

We investigated the effects of advanced glycation end products (AGE) which accumulate in
articular cartilage with age in human osteoarthritic chondrocytes. We found AGE-BSA …

Introduction Advanced glycation end products (AGEs) have been introduced to be involved
in the pathogenesis of osteoarthritis (OA). The influence of AGEs on osteoarthritic fibroblast …

Objective The major risk factor for osteoarthritis (OA) is aging, but the mechanisms
underlying this risk are only partly understood. Age‐related accumulation of advanced …

Background The advanced glycation end products (AGEs) accumulate in joints of
osteoarthritis patients. This study aimed to investigate the roles of cyclooxygenase‐2 (COX …

Accumulation of advanced glycation end products (AGEs) in joints is important in the
development of cartilage destruction and damage in age-related osteoarthritis (OA). The aim …

Objective The receptor for advanced glycation end products (RAGE) binds multiple ligands,
including S100 proteins, high mobility group box chromosomal protein 1 (HMGB‐1), and …

INTRODUCTION: During aging, advanced glycation end products (AGEs) accumulate in
articular cartilage. In this study we determined whether AGEs induce endoplasmic reticulum …