A review of synthetic bioactive tetrahydro-β-carbolines: A medicinal chemistry perspective
J Wang, F Gong, T Liang, Z Xie, Y Yang, C Cao… - European Journal of …, 2021 - Elsevier
Abstract 1, 2, 3, 4-Tetrahydro-β-carboline (THβC) scaffold is widespread in many natural
products (NPs) and synthetic compounds which show a variety of pharmacological activities …
products (NPs) and synthetic compounds which show a variety of pharmacological activities …
An overview on synthetic entries to tetrahydro-β-carbolines
P Maity, D Adhikari, AK Jana - Tetrahedron, 2019 - Elsevier
The tetrahydro-β-carboline (THBC) nucleus is a predominant feature of a vast array of
naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant …
naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant …
A comprehensive overview of β-carbolines and its derivatives as anticancer agents
B Luo, X Song - European Journal of Medicinal Chemistry, 2021 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …
diversity and outstanding antitumor activities. This review summarizes research …
Recent developments on synthesis and biological activities of γ-carboline
J Dai, W Dan, Y Zhang, J Wang - European journal of medicinal chemistry, 2018 - Elsevier
Abstract γ-Carboline alkaloids are a family of natural and synthetic agents that have diverse
bioactivities including antiviral, antibacterial, antifungal, antiparasitic, antitumor, anti …
bioactivities including antiviral, antibacterial, antifungal, antiparasitic, antitumor, anti …
β-Carboline alkaloid monomers and dimers: Occurrence, structural diversity, and biological activities
J Dai, W Dan, U Schneider, J Wang - European Journal of Medicinal …, 2018 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …
structural diversity and outstanding biological activities. This review covers critically …
Recent developments on synthesis strategies, SAR studies and biological activities of β-Carboline derivatives–an update
The β-carboline skeleton is prevalent in a vast collection of naturally present alkaloids. Most
of these alkaloids and their derivatives have been found to show significant biological …
of these alkaloids and their derivatives have been found to show significant biological …
Recent advances of natural and synthetic β-carbolines as anticancer agents
M Zhang, D Sun - Anti-Cancer Agents in Medicinal Chemistry …, 2015 - ingentaconnect.com
Cancer is a leading cause of mortality worldwide, being responsible for millions of deaths
annually. Therefore, novel cancer chemotherapeutic agents are urgently needed to combat …
annually. Therefore, novel cancer chemotherapeutic agents are urgently needed to combat …
1-Formyl-9H-β-Carboline: A Useful Scaffold for Synthesizing Substituted-and Fused β-Carbolines
1-Formyl-9H-β-Carboline: A Useful Scaffold for Synthesizing Substituted- and Fused β-Carbolines§
Page 1 Current Organic Synthesis, 2012, 9, 513-528 513 1-Formyl-9H-β-Carboline: A Useful …
Page 1 Current Organic Synthesis, 2012, 9, 513-528 513 1-Formyl-9H-β-Carboline: A Useful …
Synthesis Strategies for α‐, β‐, γ‐and δ‐Carbolines
H Zhang, RH Zhang, LX Wang, YJ Li… - Asian Journal of …, 2021 - Wiley Online Library
Carbolines are widely present in various natural products and biological molecules.
Numerous studies have shown the broad biological activities of these heterocyclic motifs …
Numerous studies have shown the broad biological activities of these heterocyclic motifs …
Recent insights into synthetic β-carbolines with anti-cancer activities
Cancer, an uncontrolled and rapid proliferation of abnormal cells, has become one of the
leading cause of death worldwide. The development of resistance among the numerous …
leading cause of death worldwide. The development of resistance among the numerous …
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