in Crystals of Deoxygenated Human Hemoglobins A, C, F, and S
JC Hanson, BC Braden - The Molecular Basis of Mutant …, 2013 - books.google.com
The predominant structure in gels and crystals of deoxy Hb S “and in sickled erythrocytes is
a half-staggered pair of strands of Hb tetramers. Similar half-staggered double strands of …
a half-staggered pair of strands of Hb tetramers. Similar half-staggered double strands of …
Contacts Between Molecular Surfaces in Crystals of Deoxygenated Human Hemoglobins A, C, F, and S
WE Love, PMD Fitzgerald, JC Hanson… - The Molecular Basis of …, 1981 - Elsevier
The predominant structure in gels and crystals of deoxy Hb S a and in sickled erythrocytes is
a half-staggered pair of strands of Hb tetramers. Similar half-staggered double strands of …
a half-staggered pair of strands of Hb tetramers. Similar half-staggered double strands of …
Flexibility of the NH,-Terminal Region of the 8 Chains of Hemoglobin: Correlation with the Gelation Properties of Deoxyhemoglobin S
A Arnone, PD Briley, PH Rogers - The Molecular Basis of Mutant …, 2013 - books.google.com
The mutation site of sickle-cell hemoglobin, residue 68, is located on the surface of each 8
chain at the boundary between the beginning of the A-helix and the NH2-terminal peptide …
chain at the boundary between the beginning of the A-helix and the NH2-terminal peptide …
Molecular properties of sickle cell hemoglobin
GL Cottam, MR Waterman - Trends in Biochemical Sciences, 1976 - cell.com
Following The First National Symposium on Sickle Cell Disease, held in July 1974 in
Washington, DC, it was clear that the molecular aspects of the aggregation of …
Washington, DC, it was clear that the molecular aspects of the aggregation of …
BIOCHEMICAL AND CLINICAL ASPECTS OF HEMOGLOBIN ABNORMALITIES
JM Quinn - Biochemical and Clinical Aspects of Hemoglobin …, 2012 - books.google.com
The reversible aggregation of deoxygenated hemoglobin S responsible for sickling of red
blood cells in sickle cell anemia is associated with formation of linear arrays or fibers of the …
blood cells in sickle cell anemia is associated with formation of linear arrays or fibers of the …
[HTML][HTML] alpha Chain mutations with opposite effects on the gelation of hemoglobin S.
RE Benesch, S Kwong, R Edalji, R Benesch - Journal of Biological …, 1979 - Elsevier
The preparation of three hemoglobin tetramers containing the hemoglobin S mutation at
beta 6 and an additional one at alpha 6, alpha 47, and alpha 75 is described. The effect of …
beta 6 and an additional one at alpha 6, alpha 47, and alpha 75 is described. The effect of …
Polymorphic Assemblies of Double Strands of Sickle Cell Hemoglobin and their Role in Fiber and Crystal Formation
R Josephs - The Molecular Basis of Mutant Hemoglobin …, 2013 - books.google.com
In vitro, concentrated solutions of deoxygenated sickle hemoglobin near physiological
conditions of pH and ionic strength form gels that consist of entangled networks of fibers.””” …
conditions of pH and ionic strength form gels that consist of entangled networks of fibers.””” …
Deoxyhemoglobin Polymerization
MMD Jones, J Steinhardt - The Molecular Basis of Mutant …, 2013 - books.google.com
The addition of normal deoxyhemoglobin (Hb" A)” and of two forms of sickle hemo-globin
(COHb and Hb") to solution of sickle deoxyhemoglobin (Hb" S) reduces the solubility of the …
(COHb and Hb") to solution of sickle deoxyhemoglobin (Hb" S) reduces the solubility of the …