Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …
dye with high structural tailorability is of great significance in the field of detection …
Hemicyanine‐based near‐infrared activatable probes for imaging and diagnosis of diseases
Molecular activatable probes with near‐infrared (NIR) fluorescence play a critical role in in
vivo imaging of biomarkers for drug screening and disease diagnosis. With structural …
vivo imaging of biomarkers for drug screening and disease diagnosis. With structural …
Coumarin-hemicyanine-based far-red to near-infrared fluorescent probes: A new generation of fluorescent probe design platform
As a classical hybrid dye, coumarin-hemicyanine dye has been widely utilized as a
remarkably powerful fluorescent imaging tool in the fields of reactive species detection …
remarkably powerful fluorescent imaging tool in the fields of reactive species detection …
An AIE-active hemicyanine fluorogen with stimuli-responsive red/blue emission: extending the pH sensing range by “switch+ knob” effect
In this work, a red-emissive zwitterionic hemicyanine dye, named TPE–Cy, containing
tetraphenylethene (TPE) and N-alkylated indolium is designed and synthesized. TPE–Cy …
tetraphenylethene (TPE) and N-alkylated indolium is designed and synthesized. TPE–Cy …
Development of photostable near-infrared cyanine dyes
With the emerging interest in optical in vivo imaging, there is an increasing demand of
photostable near-infrared (NIR) dyes. Herein we report the rational design of an amine …
photostable near-infrared (NIR) dyes. Herein we report the rational design of an amine …
Near-infrared-II cyanine/polymethine dyes, current state and perspective
The development of near-infrared-II (NIR-II) fluorescence imaging has implemented real-
time detection of biological cells, tissues and body, monitoring the disease processes and …
time detection of biological cells, tissues and body, monitoring the disease processes and …
Heptamethine cyanine dyes with a robust C− C bond at the central position of the chromophore
H Lee, JC Mason, S Achilefu - The Journal of organic chemistry, 2006 - ACS Publications
Novel, highly fluorescent, monofunctional, water-soluble heptamethine cyanine dyes
containing a robust C− C bond at the central position of the near-infrared fluorophore system …
containing a robust C− C bond at the central position of the near-infrared fluorophore system …
The pursuit of polymethine fluorophores with NIR-II emission and high brightness for in vivo applications
Polymethine cyanine dyes, as the most important class of organic near-infrared-II (NIR-II)
fluorophores, recently received increasing attention due to their high molar extinction …
fluorophores, recently received increasing attention due to their high molar extinction …
Recent progress on near‐infrared fluorescence heptamethine cyanine dye‐based molecules and nanoparticles for tumor imaging and treatment
Y Qiu, B Yuan, Y Cao, X He, OU Akakuru… - Wiley …, 2023 - Wiley Online Library
Recenly, near‐infrared fluorescence heptamethine cyanine dyes have shown satisfactory
values in bioengineering, biology, and pharmacy especially in cancer diagnosis and …
values in bioengineering, biology, and pharmacy especially in cancer diagnosis and …
Activatable Near‐Infrared Versatile Fluorescent and Chemiluminescent Dyes Based on the Dicyanomethylene‐4H‐pyran Scaffold: From Design to Imaging and …
H Li, J Wang, H Kim, X Peng… - Angewandte Chemie …, 2024 - Wiley Online Library
Activatable fluorescent and chemiluminescent dyes with near‐infrared emission have
indispensable roles in the fields of bioimaging, molecular prodrugs, and phototheranostic …
indispensable roles in the fields of bioimaging, molecular prodrugs, and phototheranostic …