While antibiotics are clearly important treatments for infection, antibiotic-induced modulation
of the immune system can have detrimental effects on pathogen clearance and immune …

Almost 140 years after its discovery, tuberculosis remains the leading infectious cause of
death globally. For half a century, patients with drug-sensitive and drug-resistant …

Antibiotics are one of the greatest discoveries of medicine of the past century. Despite their
invaluable contribution to infectious disease, their administration could lead to side effects …

Mitochondria are dynamic organelles of eukaryotes involved in energy production and fatty
acid oxidation. Besides maintaining ATP production, calcium signaling, cellular apoptosis …

This minireview explores mitochondria as a site for antibiotic-host interactions that lead to
pathophysiologic responses manifested as nonantibacterial side effects. Mitochondrion …

Antibiotics are frontline therapy against microbial infectious diseases. Many antibiotics are
known to cause several side effects in humans. Ribosomal RNA (rRNA) is the main target of …

Bactericidal antibiotics alter microbial metabolism as part of their lethality and can damage
mitochondria in mammalian cells. In addition, antibiotic susceptibility is sensitive to …

The discovery and application of antibiotics in the common clinical practice has undeniably
been one of the major medical advances in our times. Their use meant a drastic drop in …

Antibiotics had proved to be a godsend for mankind since their discovery. They were once
the magical solution to the vexing problem of infection-related deaths. German scientist Paul …

Abstract Structure and integrity of the mitochondrial network play important roles in many
cellular processes. Loss of integrity can lead to the activation of a variety of signalling …