[HTML][HTML] Analysis, identification and confirmation of synthetic opioids using chloroformate chemistry: Retrospective detection of fentanyl and acetylfentanyl in urine and …

CA Valdez, RN Leif, TH Corzett, ML Dreyer - Plos one, 2022 - journals.plos.org
Electron Impact Gas Chromatography-Mass Spectrometry (EI-GC-MS) and High Resolution
Liquid Chromatography-Mass Spectrometry (HR-LC-MS) have been used in the analysis of …

[HTML][HTML] Structural modification of fentanyls for their retrospective identification by gas chromatographic analysis using chloroformate chemistry

CA Valdez, RN Leif, RD Sanner, TH Corzett… - Scientific Reports, 2021 - nature.com
The one-step breakdown and derivatization of a panel of nine fentanyls to yield uniquely
tagged products that can be detected by Electron Ionization Gas Chromatography-Mass …

Application of the fentanyl analog screening kit toward the identification of emerging synthetic opioids in human plasma and urine by LC-QTOF

LC Krajewski, KD Swanson, WA Bragg, RL Shaner… - Toxicology letters, 2020 - Elsevier
Human exposures to fentanyl analogs, which significantly contribute to the ongoing US
opioid overdose epidemic, can be confirmed through the analysis of clinical samples. Our …

Data-independent screening method for 14 fentanyl analogs in whole blood and oral fluid using LC-QTOF-MS

KB Palmquist, MJ Swortwood - Forensic science international, 2019 - Elsevier
Recently, fentanyl analogs account for significant number of opioid deaths in the United
States. Routine forensic analyses are often unable to detect and differentiate these analogs …

Use of diagnostic ions for the detection of fentanyl analogs in human matrices by LC–QTOF

KD Swanson, RL Shaner, LC Krajewski… - Journal of the …, 2021 - ACS Publications
To combat the ongoing opioid epidemic, our laboratory has developed and evaluated an
approach to detect fentanyl analogs in urine and plasma by screening LC–QTOF MS/MS …

Analysis of fentanyl and 18 novel fentanyl analogs and metabolites by LC–MS-MS, and report of fatalities associated with methoxyacetylfentanyl and …

MF Fogarty, DM Papsun… - Journal of analytical …, 2018 - academic.oup.com
Methoxyacetylfentanyl and cyclopropylfentanyl are two of the newest illicit opioids that are
infiltrating the heroin market. Methoxyacetylfentanyl and cyclopropylfentanyl were reported …

[HTML][HTML] Development and application of a High-Resolution mass spectrometry method for the detection of fentanyl analogs in urine and serum

Y Zhang, JC Halifax, C Tangsombatvisit, C Yun… - Journal of Mass …, 2022 - Elsevier
Introduction The use of illicitly manufactured synthetic opioids, specifically fentanyl and its
analogs, has escalated exponentially in the United States over the last decade. Due to the …

Analysis of fentanyl analogs and novel synthetic opioids in blood, serum/plasma, and urine in forensic casework

MT Moody, S Diaz, P Shah, D Papsun… - Drug Testing and …, 2018 - Wiley Online Library
In recent years an increasing number of novel opioids have appeared on the illicit drug
market and have been linked to the growing opioid crisis in the United States. It is suspected …

Hitting the Jackpot–development of gas chromatography–mass spectrometry (GC–MS) and other rapid screening methods for the analysis of 18 fentanyl‐derived …

N Gilbert, LH Antonides, CJ Schofield… - Drug Testing and …, 2020 - Wiley Online Library
In recent years, the occurrence of synthetic opioid fentanyl and its derivatives has grown
significantly in forensic casework. This study presents the synthesis and analysis of 18 …

Determination of fentanyl and acetylfentanyl in soil in their intact form and orthogonal corroboration of their presence by EI-GC-MS using chloroformate chemistry

CA Valdez, JA Rosales, RN Leif - Forensic Chemistry, 2023 - Elsevier
In the field of forensic chemistry, methods for identifying and characterizing illicit drugs
remain of great interest to government and law enforcement entities. To this end, the …