Phage-specific metabolic reprogramming of virocells

C Howard-Varona, MM Lindback, GE Bastien… - The ISME …, 2020 - academic.oup.com
Ocean viruses are abundant and infect 20–40% of surface microbes. Infected cells, termed
virocells, are thus a predominant microbial state. Yet, virocells and their ecosystem impacts …

Viral metabolic reprogramming in marine ecosystems

BL Hurwitz, JM U'Ren - Current opinion in microbiology, 2016 - Elsevier
Highlights•Phages encode and express host-derived auxiliary metabolic genes
(AMGs).•AMGs encompass myriad metabolic (Class I) and peripheral (Class II) host …

Host-hijacking and planktonic piracy: how phages command the microbial high seas

J Warwick-Dugdale, HH Buchholz, MJ Allen… - Virology journal, 2019 - Springer
Microbial communities living in the oceans are major drivers of global biogeochemical
cycles. With nutrients limited across vast swathes of the ocean, marine microbes eke out a …

Phage puppet masters of the marine microbial realm

M Breitbart, C Bonnain, K Malki, NA Sawaya - Nature microbiology, 2018 - nature.com
Viruses numerically dominate our oceans; however, we have only just begun to document
the diversity, host range and infection dynamics of marine viruses, as well as the subsequent …

Virocell metabolism: metabolic innovations during host–virus interactions in the ocean

S Rosenwasser, C Ziv, SG Van Creveld, A Vardi - Trends in microbiology, 2016 - cell.com
Marine viruses are considered to be major ecological, evolutionary, and biogeochemical
drivers of the marine environment, responsible for nutrient recycling and determining …

Rising to the challenge: accelerated pace of discovery transforms marine virology

JR Brum, MB Sullivan - Nature Reviews Microbiology, 2015 - nature.com
Marine viruses have important roles in microbial mortality, gene transfer, metabolic
reprogramming and biogeochemical cycling. In this Review, we discuss recent technological …

Metabolic and biogeochemical consequences of viral infection in aquatic ecosystems

AE Zimmerman, C Howard-Varona… - Nature Reviews …, 2020 - nature.com
Ecosystems are controlled by 'bottom-up'(resources) and 'top-down'(predation) forces. Viral
infection is now recognized as a ubiquitous top-down control of microbial growth across …

Single-cell genomics-based analysis of virus–host interactions in marine surface bacterioplankton

JM Labonté, BK Swan, B Poulos, H Luo… - The ISME …, 2015 - academic.oup.com
Viral infections dynamically alter the composition and metabolic potential of marine
microbial communities and the evolutionary trajectories of host populations with resulting …

Contrasting life strategies of viruses that infect photo-and heterotrophic bacteria, as revealed by viral tagging

L Deng, A Gregory, S Yilmaz, BT Poulos, P Hugenholtz… - MBio, 2012 - Am Soc Microbiol
Ocean viruses are ubiquitous and abundant and play important roles in global
biogeochemical cycles by means of their mortality, horizontal gene transfer, and …

Dynamic marine viral infections and major contribution to photosynthetic processes shown by spatiotemporal picoplankton metatranscriptomes

ET Sieradzki, JC Ignacio-Espinoza… - Nature …, 2019 - nature.com
Viruses provide top-down control on microbial communities, yet their direct study in natural
environments was hindered by culture limitations. The advance of bioinformatics enables …