▪ Abstract Activity-dependent plasticity occurs in the spinal cord throughout life. Driven by
input from the periphery and the brain, this plasticity plays an important role in the …

Throughout normal life, activity‐dependent plasticity occurs in the spinal cord as well as in
brain. Like other central nervous system (CNS) plasticity, spinal cord plasticity can occur at …

Recovery of locomotion has been considered unattainable following a clinically complete or
severe incomplete spinal cord injury even after conventional therapy. However, the …

What is the potential for recovery of locomotor ability after a spinal cord injury? Both human
and animal studies show that the spinal cord has the potential to reorganize and/or readjust …

Functional recovery after CNS injury may depend, in part, upon reorganization of
undamaged neural pathways. Spinal cord circuits are capable of significant reorganization …

New appreciation of the adaptive capabilities of the nervous system, recent recognition that
most spinal cord injuries are incomplete, and progress in enabling regeneration are …

Spinal cord injury results in marked modification and reorganization of several reflex
pathways caudal to the injury. The sudden loss or disruption of descending input engenders …

▪ Abstract Motor function is severely disrupted following spinal cord injury (SCI). The spinal
circuitry, however, exhibits a great degree of automaticity and plasticity after an injury …

Synaptic plasticity within the spinal cord has great potential to facilitate recovery of function
after spinal cord injury (SCI). Spinal plasticity can be induced in an activity-dependent …

Motor, sensory, and autonomic functions can spontaneously return or recover to varying
extents in both humans and animals, regardless of the traumatic spinal cord injury (SCI) …