Mass spectrometry imaging (MSI) has seen remarkable development in recent years. The
possibility of getting quantitative or semiquantitative data, while maintaining the spatial …

In the past decade, mass spectrometry imaging (MSI) has received an increasing amount of
attention due to its ability in displaying the spatial distribution of a wide range of molecules …

Highlights•Mass spectrometric imaging is a new imaging tool.•It is also a new technique
available for pharmacokinetics studies.•Images of molecular distribution inside tissues slices …

Mass spectrometry imaging (MSI) is a rapidly evolving technology that yields qualitative and
quantitative distribution maps of small pharmaceutical-active molecules and their …

Highlights•An overview of recent advances in MSI for drug localization is presented.•MSI
provides label-free imaging of drugs and metabolites at high lateral resolution.•Spatial …

The emerging and powerful field of spatial pharmacology can map the spatial distribution of
drugs and their metabolites, as well as their effects on endogenous biomolecules including …

Mass spectrometry imaging (MSI) is emerging as a powerful analytical tool for detection,
quantification, and simultaneous spatial molecular imaging of endogenous and exogenous …

Since its introduction mass spectrometry imaging (MSI) has proven to be a powerful tool for
the localization of molecules in biological tissues. In drug discovery and development …

Mass spectrometry (MS) imaging is a versatile method to analyze the spatial distribution of
analytes in tissue sections. It provides unique features for the analysis of drug compounds in …

Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …