Spermatozoa released from the testis are unable to fertilize an egg without a coordinated
process of maturation in the lumen of the epididymis. Relatively little is known about the …

The epithelium lining the epididymis has a pivotal role in ensuring a luminal environment
that can support normal sperm maturation. Many of the individual genes that encode …

Once shed from their fostering Sertoli cells, spermatozoa leave the testis and are transported
passively by seminiferous fluid through the rete testis. Then, these immature cells enter the …

STUDY HYPOTHESIS Region-specific transcriptional profiling of tissues and cultured
epithelial cells from the human epididymis will predict functional specialization along the …

Background The epithelial lining of the human epididymis is critical for sperm maturation.
This process requires distinct specialized functions in the head, body, and tail of the duct …

Following testicular spermatogenesis, mammalian sperm continue to mature in a long
epithelial tube known as the epididymis, which plays key roles in remodeling sperm protein …

Maturation of spermatozoa, including the acquisition of motility and the ability to undergo
capacitation, occurs during transit through the dynamic environment of the epididymis. The …

During their transit through the epididymis, spermatozoa undergo many biochemical
modifications necessary to acquire flagellar motility and fertilizing ability. These …

Spermatozoa acquire their fertilizing ability and forward motility during epididymal transit,
suggesting the importance of the epididymis. Although the cell atlas of the epididymis was …

BACKGROUND Spermatozoa acquire their fertilizing ability and forward motility properties
during epididymal transit. Our knowledge of gamete physiology is based on studies …