Comment on: Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with COPD: a systematic review …

P Almagro, P Martinez-Camblor - European Respiratory …, 2023 - Eur Respiratory Soc
We read with great interest the meta-analysis recently published in the European
Respiratory Journal by Yang et al.[1] concerning the risk of major adverse cardiovascular …

Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events

S Suissa, S Dell'Aniello, P Ernst - European Respiratory …, 2017 - Eur Respiratory Soc
The cardiovascular risk of concurrently using long-acting β2-agonists (LABAs) and
anticholinergics (LAMAs) in COPD is uncertain. We assessed the comparative …

Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with COPD: a systematic review and meta …

M Yang, Y Li, Y Jiang, S Guo, JQ He… - European Respiratory …, 2023 - Eur Respiratory Soc
Introduction Accumulated high-quality data from randomised controlled trials (RCTs)
indicate that long-acting muscarinic antagonist (LAMA)/long-acting β2 agonist (LABA) …

Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

A Manoharan, PM Short, WJ Anderson, BJ Lipworth - Lung, 2014 - Springer
Introduction We performed a real-life retrospective analysis to assess the impact of long-
acting bronchodilator therapy and associated exposure to inhaled corticosteroids (ICS) on …

Effectiveness and safety of concurrent beta-blockers and inhaled bronchodilators in COPD with cardiovascular comorbidities

S Corrao, G Brunori, U Lupo… - European Respiratory …, 2017 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is the most common chronic respiratory
disease and its prevalence is increasing worldwide, in both industrialised and developing …

[引用][C] Combining dual bronchodilation and β-blockade in patients with an overlap between COPD and cardiovascular diseases

M Cazzola, MG Matera - Chest, 2018 - journal.chestnet.org
The well-established overlap between COPD and cardiovascular diseases (CVDs) suggests
that there is a strong need for COPD and CVD to be considered in an integrated way, 1 …

Triple therapy versus dual bronchodilation and inhaled corticosteroids/long-acting β-agonists in COPD: accumulating evidence from network meta-analyses

M Cazzola, L Calzetta, P Rogliani, MG Matera - Pulmonary Therapy, 2019 - Springer
Guidelines are mainly based on evidence of well-designed randomized controlled trials
(RCTs), but there are limitations to the transferability of conclusions of RCTs to usual care …

The Therapeutic Index as Indicated by Efficacy/Safety Ratio May Be Primarily Assessed by Meta-Analysis of the Efficacy of ICS Combination Therapy for COPD

S Teramoto - … Journal of Chronic Obstructive Pulmonary Disease, 2022 - Taylor & Francis
With interest, we read the review article by Ding et al 1 published in the recent issue of the
International Journal of Chronic Obstructive Pulmonary Disease (COPD). They performed a …

COPD and bronchodilators: should the heart pay the bill for the lung?

N Agabiti, GM Corbo - European Respiratory Journal, 2017 - Eur Respiratory Soc
The pharmacological treatment of patients with coexisting cardiovascular disease (CVD)
and chronic obstructive pulmonary disease (COPD) is challenging, because some drugs for …

Rebuttal From Drs Cazzola and Matera

M Cazzola, MG Matera - Chest, 2018 - journal.chestnet.org
The motivations given by Barrecheguren and Miravitlles 1 against the need to use dual
bronchodilation on diagnosis of COPD are scientifically sound and pragmatic. However, the …