The interplay between insulin resistance, inflammation, oxidative stress, base excision repair and metabolic syndrome in nonalcoholic fatty liver disease

S Ziolkowska, A Binienda, M Jabłkowski… - International journal of …, 2021 - mdpi.com
One of the most common chronic liver disorders, affecting mainly people in Western
countries, is nonalcoholic fatty liver disease (NAFLD). Unfortunately, its pathophysiological …

The role of insulin resistance and diabetes in nonalcoholic fatty liver disease

H Fujii, N Kawada… - International journal of …, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) consists of the entire spectrum of fatty liver disease
in patients without significant alcohol consumption, ranging from nonalcoholic fatty liver …

Role of insulin resistance in MAFLD

Y Sakurai, N Kubota, T Yamauchi… - International journal of …, 2021 - mdpi.com
Many studies have reported that metabolic dysfunction is closely involved in the complex
mechanism underlying the development of non-alcoholic fatty liver disease (NAFLD), which …

Bidirectional relationships and disconnects between NAFLD and features of the metabolic syndrome

P Wainwright, CD Byrne - International journal of molecular sciences, 2016 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) represents a wide spectrum of liver disease from
simple steatosis, to steatohepatitis,(both with and without liver fibrosis), cirrhosis and end …

Lipotoxicity as the leading cause of non-alcoholic steatohepatitis

M Branković, I Jovanović, M Dukić, T Radonjić… - International Journal of …, 2022 - mdpi.com
The emerging issues nowadays are non-alcoholic fatty liver disease (NAFLD) and its
advanced stage non-alcoholic steatohepatitis (NASH), which further can be a predisposing …

Mitochondrial dysfunction plays central role in nonalcoholic fatty liver disease

R Ramanathan, AH Ali, JA Ibdah - International Journal of Molecular …, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a global pandemic that affects one-quarter of the
world's population. NAFLD includes a spectrum of progressive liver disease from steatosis to …

Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines

SA Polyzos, J Kountouras… - Current molecular …, 2009 - ingentaconnect.com
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of common hepatic
disorders in western countries, with multiple consequences and its incidence is paralleling …

Mechanisms of non-alcoholic fatty liver disease in the metabolic syndrome. A narrative review

L Rinaldi, PC Pafundi, R Galiero, A Caturano… - Antioxidants, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are two different
entities sharing common clinical and physio-pathological features, with insulin resistance …

Pathophysiological, molecular and therapeutic issues of nonalcoholic fatty liver disease: an overview

S Marchisello, A Di Pino, R Scicali, F Urbano… - International journal of …, 2019 - mdpi.com
Nonalcoholic Fatty Liver Disease (NAFLD) represents the leading cause of liver disease in
developed countries but its diffusion is currently also emerging in Asian countries, in South …

Immunity as cornerstone of non-alcoholic fatty liver disease: the contribution of oxidative stress in the disease progression

M Dallio, M Sangineto, M Romeo, R Villani… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of
metabolic syndrome and has become the major cause of chronic liver disease, especially in …