High‐accuracy protein structure prediction in CASP14

J Pereira, AJ Simpkin, MD Hartmann… - Proteins: Structure …, 2021 - Wiley Online Library
The application of state‐of‐the‐art deep‐learning approaches to the protein modeling
problem has expanded the “high‐accuracy” category in CASP14 to encompass all targets …

Evaluation of predictions in the CASP10 model refinement category

T Nugent, D Cozzetto, DT Jones - Proteins: Structure, Function …, 2014 - Wiley Online Library
Here we report on the assessment results of the third experiment to evaluate the state of the
art in protein model refinement, where participants were invited to improve the accuracy of …

CASP9 assessment of free modeling target predictions

L Kinch, S Yong Shi, Q Cong, H Cheng… - Proteins: Structure …, 2011 - Wiley Online Library
We present an overview of the ninth round of Critical Assessment of Protein Structure
Prediction (CASP9)“Template free modeling” category (FM). Prediction models were …

Continuous Automated Model EvaluatiOn (CAMEO) complementing the critical assessment of structure prediction in CASP12

J Haas, A Barbato, D Behringer… - Proteins: Structure …, 2018 - Wiley Online Library
Every second year, the community experiment “Critical Assessment of Techniques for
Structure Prediction”(CASP) is conducting an independent blind assessment of structure …

Improved protein structure prediction using potentials from deep learning

AW Senior, R Evans, J Jumper, J Kirkpatrick, L Sifre… - Nature, 2020 - nature.com
Protein structure prediction can be used to determine the three-dimensional shape of a
protein from its amino acid sequence. This problem is of fundamental importance as the …

Improved protein structure prediction using predicted interresidue orientations

J Yang, I Anishchenko, H Park… - Proceedings of the …, 2020 - National Acad Sciences
The prediction of interresidue contacts and distances from coevolutionary data using deep
learning has considerably advanced protein structure prediction. Here, we build on these …

Critical assessment of methods of protein structure prediction (CASP)—Round XIV

A Kryshtafovych, T Schwede, M Topf… - Proteins: Structure …, 2021 - Wiley Online Library
Critical assessment of structure prediction (CASP) is a community experiment to advance
methods of computing three‐dimensional protein structure from amino acid sequence. Core …

Protein structure prediction using multiple deep neural networks in the 13th Critical Assessment of Protein Structure Prediction (CASP13)

AW Senior, R Evans, J Jumper… - Proteins: structure …, 2019 - Wiley Online Library
We describe AlphaFold, the protein structure prediction system that was entered by the
group A7D in CASP13. Submissions were made by three free‐modeling (FM) methods …

Topology evaluation of models for difficult targets in the 14th round of the critical assessment of protein structure prediction (CASP14)

LN Kinch, J Pei, A Kryshtafovych… - Proteins: Structure …, 2021 - Wiley Online Library
This report describes the tertiary structure prediction assessment of difficult modeling targets
in the 14th round of the Critical Assessment of Structure Prediction (CASP14). We …

Analysis of distance‐based protein structure prediction by deep learning in CASP13

J Xu, S Wang - Proteins: Structure, Function, and Bioinformatics, 2019 - Wiley Online Library
This paper reports the CASP13 results of distance‐based contact prediction, threading, and
folding methods implemented in three RaptorX servers, which are built upon the powerful …